CAJ | 학술논문

目的：探讨检测2型糖尿病视网膜病变患者血清C肽水平的价值。方法：收集2010年11月至2013年11月收治的180例2型糖尿病患者，根据视网膜病变分为增值性糖尿病视网膜病变（PDR）组60例、非增值性糖尿病视网膜病变（NPDR）组60例和无糖尿病视网膜病变（NDR）组60例，用电化学发光方法检测三组患者空腹血清C肽和血糖水平，分析各项因素与视网膜病变的关系。结果：PDR组、NPDR组、NDR组C肽水平分别为（0.58±0.31）、（1.43±0.66）、（2.12±0.82）ng/ml，组间差异有统计学意义（P＜0.05）。C肽水平与糖尿病视网膜病变呈负相关。结论：检测2型糖尿病视网膜病变患者C肽水平，有助于及时预防和治疗视网膜病变。
목적：탐토검측2형당뇨병시망막병변환자혈청C태수평적개치。방법：수집2010년11월지2013년11월수치적180례2형당뇨병환자，근거시망막병변분위증치성당뇨병시망막병변（PDR）조60례、비증치성당뇨병시망막병변（NPDR）조60례화무당뇨병시망막병변（NDR）조60례，용전화학발광방법검측삼조환자공복혈청C태화혈당수평，분석각항인소여시망막병변적관계。결과：PDR조、NPDR조、NDR조C태수평분별위（0.58±0.31）、（1.43±0.66）、（2.12±0.82）ng/ml，조간차이유통계학의의（P＜0.05）。C태수평여당뇨병시망막병변정부상관。결론：검측2형당뇨병시망막병변환자C태수평，유조우급시예방화치료시망막병변。
Objective:To explore the application value of the determination of the C peptide level in the patients with the type 2 diabetic retinopathy. Methods:One hundred and eighty patients who were treated in the hospital from Nov. 2010 to Nov. 2013 were selected and divided into a group of value added of diabetic retinopathy (PDR), a group of non value added diabetic retinopathy (NPDR), and a group of no diabetic retinopathy (NDR) with 60 patients each according to retinopathy. The electrochemical luminescence method was used to determine the serum C peptide and blood sugar level and the relationship of the variety factors with retinopathy was analyzed. Results:The C peptide levels in the PDR group, NPDR one, and NDR one were (0.58±0.31), (1.43±0.66), and (2.12±0.82)ng/ml, respectively and the differences among groups had the statistical differences (P<0.05). The C peptide level had the negative correlation with diabetic retinopathy. Conclusion:The determination of the C peptide level in the patients with the type 2 diabetic retinopathy is of beneift to the timely prevention and treatment of the retinal lesions.