CAJ | 학술논문

目的：探讨高频振荡通气（ HFOV）对新生儿呼吸窘迫综合征（ NRDS）的治疗效果。方法选取2012－04～2014－05间我院收治的80例NRDS患儿，将其随机分为观察组和对照组。对照组采用常频机械通气（ CMV）治疗，观察组采用HFOV治疗，比较两组患儿的治疗效果及并发症。结果观察组机械通气24 h后呼吸机参数FiO2、MAP、OI值均低于对照组，血气分析中PCO2值高于对照组，两组比较差异有统计学意义（ P＜0．05）；观察组吸氧时间、机械通气时间及住院时间均短于对照组，差异有统计学意义（ P＜0．05）；观察组并发症发生率为2．50％，明显低于对照组（20．00％），差异有统计学意义（ P＜0．05）。结论高频振荡通气治疗新生儿呼吸窘迫综合征，可改善患儿通气，缩短机械通气时间，减少并发症发生，具有显著临床治疗效果。
목적：탐토고빈진탕통기（ HFOV）대신생인호흡군박종합정（ NRDS）적치료효과。방법선취2012－04～2014－05간아원수치적80례NRDS환인，장기수궤분위관찰조화대조조。대조조채용상빈궤계통기（ CMV）치료，관찰조채용HFOV치료，비교량조환인적치료효과급병발증。결과관찰조궤계통기24 h후호흡궤삼수FiO2、MAP、OI치균저우대조조，혈기분석중PCO2치고우대조조，량조비교차이유통계학의의（ P＜0．05）；관찰조흡양시간、궤계통기시간급주원시간균단우대조조，차이유통계학의의（ P＜0．05）；관찰조병발증발생솔위2．50％，명현저우대조조（20．00％），차이유통계학의의（ P＜0．05）。결론고빈진탕통기치료신생인호흡군박종합정，가개선환인통기，축단궤계통기시간，감소병발증발생，구유현저림상치료효과。
Objective To investigate the treatment effect of high frequency oscillation ventilation ( HFOV) for neonatal respiratory dis-tresssyndrome(NRDS).Methods 80neonateswithNRDSwereselectedfromthehospitalfromApril,2012toMay,2014,andwere assigned to the observation group and the control group randomly .The observation group were treated with HFOV while the control group were treated with conventional mechanical ventilation ( CMV ) .The treatment effect and complication were compared between the two groups.Results The value of FiO2 , MAP and OI of observation group after 24 hours mechanical ventilation were all lower than those of control group , while the value of PCO 2 of observation group was higher than that of control group , with statistical significance ( P<0.05 ) . The duration of oxygen uptake , mechanical ventilation and hospitalization of observation group were shorter than those of control group ( P<0.05).The complication incidence of observation group and control group were 2.50%and 20.00%, respectively.The complication in-cidence of observation group was apparently lower than that of control group (P<0.05).Conclusion HFOV in treatment of NRDS can im-prove the ventilation of neonates , shorten the duration of mechanical ventilation and reduce the complication incidence , which has a signifi-cant clinical treatment effect .