CAJ | 학술논문

目的：探讨实施育龄妇女孕前风险评估对降低出生缺陷的干预效果。方法选择在我院进行免费孕前筛查的650例育龄妇女为干预组，进行孕前风险评估；随机抽取650例在县人民医院住院分娩，且未进行孕前风险评估的产妇为对照组。比较两组观察对象优生知识知晓情况、孕期营养指导、叶酸服用及出生缺陷发生情况等。结果干预组对象优生知识知晓率、孕期营养指导率、叶酸服用率均明显优于对照组，差异有统计学意义（ P＜0．05）。干预组围产儿出生缺陷的发生率为4．6‰（3／650），明显低于对照组的12．3‰（8／650），差异具有统计学意义（ P＜0．05）。结论孕前风险评估可有效识别出育龄妇女自身存在的危险因素，通过采取有针对性的干预，有效降低了出生缺陷率。
목적：탐토실시육령부녀잉전풍험평고대강저출생결함적간예효과。방법선택재아원진행면비잉전사사적650례육령부녀위간예조，진행잉전풍험평고；수궤추취650례재현인민의원주원분면，차미진행잉전풍험평고적산부위대조조。비교량조관찰대상우생지식지효정황、잉기영양지도、협산복용급출생결함발생정황등。결과간예조대상우생지식지효솔、잉기영양지도솔、협산복용솔균명현우우대조조，차이유통계학의의（ P＜0．05）。간예조위산인출생결함적발생솔위4．6‰（3／650），명현저우대조조적12．3‰（8／650），차이구유통계학의의（ P＜0．05）。결론잉전풍험평고가유효식별출육령부녀자신존재적위험인소，통과채취유침대성적간예，유효강저료출생결함솔。
Objective To investigate the effect of intervention on implementation of pre pregnant women risk assessment on the effect of thebirthdefects.Methods 650casesofreproductiveagewomenoffreescreeningbeforepregnancyinthehospitalwereselectedasthein-tervention group , and the pre pregnancy risk assessment on them was done .650 patients in county -level people′s hospital who did not carry out pre pregnancy risk assessment were randomly selected as the control group .The eugenic knowledge , nutrition guidance during pregnancy , folic acid and birth defects incidence between the two groups were compared .Results Through comparing with the control group , the eugenic knowledge rate , nutrition guidance during pregnancy rate , the rate of folic acid in the intervention group were significant-ly better than that of the control group , and the difference was statistically significant (P<0.05).The perinatal birth defects incidence rate of intervention group was 4.6‰(3/650), and it was significantly lower than that of the control group of 12.3‰(8/650), with significant difference (P<0.05).Conclusion The pre pregnancy risk assessment can effectively identify the risk factors for women of childbearing age in the existence of their own , through targeted intervention , which can effectively reduce the incidence of birth defects .