CAJ | 학술논문

目的:研究同型半胱氨酸诱导基因(HCY-2)在发育不同时期的正常人胚气管和肺中的表达,揭示HCY-2基因在呼吸系统发育中的作用.方法:取正常人胚气管和肺,采用免疫组织化学ABC法对气管和肺内HCY-2表达变化进行分析.结果:HCY-2在人胚气管和肺发育的整个时期均表达,其表达部位主要在气管及其各级支气管的上皮和气管腺腺细胞内.结论:HCY-2表达蛋白可能与人胚气管及肺的发育密切相关.
목적:연구동형반광안산유도기인(HCY-2)재발육불동시기적정상인배기관화폐중적표체,게시HCY-2기인재호흡계통발육중적작용.방법:취정상인배기관화폐,채용면역조직화학ABC법대기관화폐내HCY-2표체변화진행분석.결과:HCY-2재인배기관화폐발육적정개시기균표체,기표체부위주요재기관급기각급지기관적상피화기관선선세포내.결론:HCY-2표체단백가능여인배기관급폐적발육밀절상관.
Objective:To investigate the expression of homocysteine induced gene(HCY-2)in the normal human embryonic trachea and lung and to reveal the effects of HCY-2 on the development of respiration system. Methods: The immunohistochemistry ABC method was used to detect the HCY-2 expression in the normal human embryonic trachea and lung. Results:HCY-2 expressed during the whole development of the human embryonic trachea and lung and mainly in the epitheliums of trachea and pulmonary bronchi and glandular epitheliums. Conclusion:HCY-2 expression protein could be closely related to the development of trachea and lung.