CAJ | 학술논문

目的：探讨急性ST段抬高型心肌梗死（STEMI）患者外周血白细胞（WBC）计数与肌钙蛋白I（cTnI）、N端B型脑钠肽前体（NT－proBNP）的关系。方法选择STEMI患者146例，依据白细胞计数水平分为白细胞升高组（WBC＞10×109／L）和白细胞正常组（WBC≤10×109／L），比较两组患者的临床特征，测定两组患者cTnI、NT－proBNP水平并进行比较。结果与WBC正常组比较，WBC升高组患者的cTnI、NT－proBNP水平显著升高，WBC升高程度与cTnI、NT－proBNP水平呈正相关。结论 STEMI患者的外周血白细胞水平与cTnI、N端B型脑钠肽前体水平密切相关，WBC作为炎症指标可间接反映心肌梗死的面积和程度。
목적：탐토급성ST단태고형심기경사（STEMI）환자외주혈백세포（WBC）계수여기개단백I（cTnI）、N단B형뇌납태전체（NT－proBNP）적관계。방법선택STEMI환자146례，의거백세포계수수평분위백세포승고조（WBC＞10×109／L）화백세포정상조（WBC≤10×109／L），비교량조환자적림상특정，측정량조환자cTnI、NT－proBNP수평병진행비교。결과여WBC정상조비교，WBC승고조환자적cTnI、NT－proBNP수평현저승고，WBC승고정도여cTnI、NT－proBNP수평정정상관。결론 STEMI환자적외주혈백세포수평여cTnI、N단B형뇌납태전체수평밀절상관，WBC작위염증지표가간접반영심기경사적면적화정도。
Objective To evaluate the correlation between peripheral white blood cell ( WBC) count and cardiac troponin I ( cTnI) and N-terminal pro-B-type natriuretic peptide(NT-proBNP )in acute ST-elevated myocardial infarction(STEMI) patients.Methods A total of 146 patients with acute STEMI were categorized into WBC elevated group (WBC>10 ×109/L)and WBC normal group(WBC≤10 ×109/L) according to the levels of WBC .Clinical characteristics were compared between the two groups .The levels of WBC ,cTnI and NT-proBNP were measured in all patients .Results Compared with WBC normal group ,cTnI and NT-proBNP levels were significantly elevated in elevated group .There were the positive correlation between WBC count and cTnI ,and NT-proBNP levels.Conclusion The WBC level of acute STEMI patients is closely associated with cTnI and NT -proBNP levels.WBC as inflammatory markers may indirectly reflect the size and severity of myocardial infarction with acute STEMI patients .