当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2015年
13期
152-153
,共2页
非酒精性脂肪性肝炎%中医%临床疗效
非酒精性脂肪性肝炎%中醫%臨床療效
비주정성지방성간염%중의%림상료효
Nonalcoholic steatohepatitis%Traditional Chinese medicine%Clinical efficacy
目的 探讨中医优化方案治疗非酒精性脂肪性肝炎(NASH)的临床疗效.方法 选择NASH患者104例,随机分为观察组与对照组,各52例.对照组予以多烯磷脂酰胆碱胶囊治疗,观察组予以化痰利湿活血方基本方颗粒剂联合加减方颗粒剂治疗,比较2组的临床疗效.结果 治疗后观察组的谷丙转氨酶(ALT)及甘油三酯(TG)分别为(35.49±18.33)mmol/L、(1.60±0.87)mmol/L,均显著低于对照组的(53.94±41.42)mmol/L、(2.02±1.15)mmol/L(P<0.05),观察组肝脾CT值为(0.99±0.18)HU,显著高于对照组的(0.82±0.21)HU(P<0.05);观察组的证候积分为(3.69±3.21)分,显著低于对照组的(8.01±5.78)分(P<0.05);观察组的治疗总有效率为98.1%,显著高于对照组的80.8%(P<0.05).结论 中医优化方案治疗NASH疗效显著.
目的 探討中醫優化方案治療非酒精性脂肪性肝炎(NASH)的臨床療效.方法 選擇NASH患者104例,隨機分為觀察組與對照組,各52例.對照組予以多烯燐脂酰膽堿膠囊治療,觀察組予以化痰利濕活血方基本方顆粒劑聯閤加減方顆粒劑治療,比較2組的臨床療效.結果 治療後觀察組的穀丙轉氨酶(ALT)及甘油三酯(TG)分彆為(35.49±18.33)mmol/L、(1.60±0.87)mmol/L,均顯著低于對照組的(53.94±41.42)mmol/L、(2.02±1.15)mmol/L(P<0.05),觀察組肝脾CT值為(0.99±0.18)HU,顯著高于對照組的(0.82±0.21)HU(P<0.05);觀察組的證候積分為(3.69±3.21)分,顯著低于對照組的(8.01±5.78)分(P<0.05);觀察組的治療總有效率為98.1%,顯著高于對照組的80.8%(P<0.05).結論 中醫優化方案治療NASH療效顯著.
목적 탐토중의우화방안치료비주정성지방성간염(NASH)적림상료효.방법 선택NASH환자104례,수궤분위관찰조여대조조,각52례.대조조여이다희린지선담감효낭치료,관찰조여이화담리습활혈방기본방과립제연합가감방과립제치료,비교2조적림상료효.결과 치료후관찰조적곡병전안매(ALT)급감유삼지(TG)분별위(35.49±18.33)mmol/L、(1.60±0.87)mmol/L,균현저저우대조조적(53.94±41.42)mmol/L、(2.02±1.15)mmol/L(P<0.05),관찰조간비CT치위(0.99±0.18)HU,현저고우대조조적(0.82±0.21)HU(P<0.05);관찰조적증후적분위(3.69±3.21)분,현저저우대조조적(8.01±5.78)분(P<0.05);관찰조적치료총유효솔위98.1%,현저고우대조조적80.8%(P<0.05).결론 중의우화방안치료NASH료효현저.
Objective To investigate the clinical efficacy of traditional Chinese medicine optimization program for the treatment of patients with non-alcoholic steatohepatitis (NASH).Methods 104 NASH patients were randomly divided into observation group and control group, 52 cases in each. The control group received polyene phosphatidylcholine capsule treatment, the observation group received Huatan Lishi Huoxue granule combined granule decoction treatment, the clinical efficacy of two groups were compared.Results After treatment,the ALT and TG of the observation group was (35.49±18.33)mmol/L, (1.60±0.87)mmol/L, significantly lower than (53.94±41.42)mmol/L and (2.02±1.15)mmol/L of the control group (P<0.05), the liver and spleen CT value of the observation group was (0.99±0.18)HU, significantly higher than the (0.82±0.21)HU of control group (P<0.05); the symptom score of the observation group was (3.69±3.21), significantly lower than the (8.01±5.78) of control group (P<0.05); the total efficiency of observation group was 98.1%, significantly lower than 80.8% in the control group (P<0.05).Conclusion Traditional Chinese medicine optimization program for the treatment of NASH has a significant effect
