CAJ | 학술논문

以壳聚糖（CTS）和双氰胺为原料，在一定温度下通过亲核加成合成壳聚糖双胍盐酸盐（CGH）衍生物， CGH 与不同浓度的碘乙醇溶液制备改性壳聚糖的碘络合物（CGH-I2）。用 IR 光谱、XRD、TG 和 DTG 对衍生物进行表征，通过碘量法测 CGH 与碘络合的质量比。碘含量分析表明：碘乙醇溶液浓度为0.02mol/L 时，CGH 与碘络合的最大质量比为 m(CGH)∶m(I2)=1∶0.46。抑菌性测试表明：CGH-I2对大肠杆菌和金黄色葡萄球菌抑菌环直径分别为(18±1)mm 和(21±1)mm，敏感度均为高度敏感。
이각취당（CTS）화쌍청알위원료，재일정온도하통과친핵가성합성각취당쌍고염산염（CGH）연생물， CGH 여불동농도적전을순용액제비개성각취당적전락합물（CGH-I2）。용 IR 광보、XRD、TG 화 DTG 대연생물진행표정，통과전량법측 CGH 여전락합적질량비。전함량분석표명：전을순용액농도위0.02mol/L 시，CGH 여전락합적최대질량비위 m(CGH)∶m(I2)=1∶0.46。억균성측시표명：CGH-I2대대장간균화금황색포도구균억균배직경분별위(18±1)mm 화(21±1)mm，민감도균위고도민감。
A novel derivative,chitosan biguanide hydrochloride (CGH),was synthesized by using chitosan (CTS) and dicyandiamide in a simple nucleophilic addition process at a certain temperature. Then,the complex compound (CGH-I2) was obtained by immersing CGH in iodine ethanol solution with different concentrations. The properties of CGH were characterized by means of IR,XRD,TG and DTG. The analysis of iodine content shows that the maximum mass ratio of CGH complex with iodine was m (CGH)∶m (I2) =1∶0. 46 when the concentration of iodine ethanol solution was 0.02mol/L. The antimicrobial test results show that the antibacterial diameters of the CGH-I2 against E. coli and Staphylococcus aureus were (18±1)mm and (21±1)mm respectively,with a high sensitivity of bacteriostasis.