当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2015年
13期
53-54
,共2页
A2B亚型%抗-A1抗体%血型鉴定%交叉配血
A2B亞型%抗-A1抗體%血型鑒定%交扠配血
A2B아형%항-A1항체%혈형감정%교차배혈
Subgroups of A2B%Anti-A1%Blood group test%Cross matching
目的 探讨A2B亚型输血相容性检测结果及其配合型输血方案选择.方法 运用三步法分析血型鉴定正反定型不符的血样本.在不同试验条件下,进行ABO血型鉴定相关血型血清学实验;盐水法、微柱凝胶抗人球蛋白介质法进行交叉配血试验.结果 发现1例患者血型血清学试验反应格局符合A2B亚型,同时含有高效价IgM抗-A1抗体.采用O型洗涤红细胞配合型输血,未发生输血不良反应,输血疗效良好.结论 ABO血型鉴定正反定型不符时,应考虑有可能为ABO亚型;A 2 B亚型可伴有IgM抗-A 1抗体产生;不规则抗体筛查试验所用谱细胞为O细胞制备,不含有A、B抗原,不能检出ABO亚型中含有的不规则抗-A、抗-B抗体;A 2 B亚型患者选择配合型输血,输血疗效良好.
目的 探討A2B亞型輸血相容性檢測結果及其配閤型輸血方案選擇.方法 運用三步法分析血型鑒定正反定型不符的血樣本.在不同試驗條件下,進行ABO血型鑒定相關血型血清學實驗;鹽水法、微柱凝膠抗人毬蛋白介質法進行交扠配血試驗.結果 髮現1例患者血型血清學試驗反應格跼符閤A2B亞型,同時含有高效價IgM抗-A1抗體.採用O型洗滌紅細胞配閤型輸血,未髮生輸血不良反應,輸血療效良好.結論 ABO血型鑒定正反定型不符時,應攷慮有可能為ABO亞型;A 2 B亞型可伴有IgM抗-A 1抗體產生;不規則抗體篩查試驗所用譜細胞為O細胞製備,不含有A、B抗原,不能檢齣ABO亞型中含有的不規則抗-A、抗-B抗體;A 2 B亞型患者選擇配閤型輸血,輸血療效良好.
목적 탐토A2B아형수혈상용성검측결과급기배합형수혈방안선택.방법 운용삼보법분석혈형감정정반정형불부적혈양본.재불동시험조건하,진행ABO혈형감정상관혈형혈청학실험;염수법、미주응효항인구단백개질법진행교차배혈시험.결과 발현1례환자혈형혈청학시험반응격국부합A2B아형,동시함유고효개IgM항-A1항체.채용O형세조홍세포배합형수혈,미발생수혈불량반응,수혈료효량호.결론 ABO혈형감정정반정형불부시,응고필유가능위ABO아형;A 2 B아형가반유IgM항-A 1항체산생;불규칙항체사사시험소용보세포위O세포제비,불함유A、B항원,불능검출ABO아형중함유적불규칙항-A、항-B항체;A 2 B아형환자선택배합형수혈,수혈료효량호.
Objective To report a example of subgroups of A2B about the transfusion compatibility testing results and the cooperate blood transfusion select.Methods Analyze the sample inconformity with forward typing and reverse typing of blood grouping with three-step process. Do experiments of blood group serologic investigation at different condition; Do cross matching test with NS method and Anti globulin medium micro column gel method.Results The blood group serological investigations results of one patient's are correspond with subgroups of A2B and this patient's blood is also contains high potency IgM antibody of anti-A1. Transfusion with washed RBC of group O, no adverse reaction was observed, curative effect is good.Conclusion We should consider the subgroups of ABO when it is inconformity with forward typing and reverse typing of blood grouping, subgroups of A2B may produce IgM antibody of anti-A1. The panel cell in the unexpected antibodies test are extraction by O cell, so it doesn't have A antigen and B antigen , and couldn't ifnd the unexpected anti-A and anti-B of ABO blood group system. Patients of subgroups of A2B can choose cooperate blood transfusion which has excellent curative effective.
