CAJ | 학술논문

目的：探讨膝骨性关节炎(KOA)疼痛程度与MRI软骨下骨髓水肿(BME)程度的相关性。方法：KOA 142例按疼痛程度分为无疼痛组31例、疼痛1级组86例、疼痛2级组25例，将其MRI骨髓水肿分为0级(无骨髓水肿)38例、1级(轻度骨髓水肿)69例、2级(较大骨髓水肿)35例，将疼痛程度与KOA骨髓水肿分级进行χ2检验，并将疼痛各组与水肿分级进行多个独立样本比较的秩和检验。结果：无疼痛组29.1％(9/31例)存在BME，疼痛1级组82.6％(71/86例)存在BME，疼痛2级组92％(24/25例)存在BME；无疼痛组与疼痛1级组、疼痛2级组相比差异有统计学意义(χ2=12.613，P＜0.001；χ2=14.535，P＜0.001)，多个独立样本比较的秩和检验显示，3组BME差异有统计学意义(P＜0.001)，随疼痛的加重，BME分级的平均秩次逐渐加大(0级、1级和2级分别为79.12、102.82和139.26)。结论：KOA疼痛与软骨下骨髓水肿相关，且存在疼痛越重、骨髓水肿越严重的趋势。
목적：탐토슬골성관절염(KOA)동통정도여MRI연골하골수수종(BME)정도적상관성。방법：KOA 142례안동통정도분위무동통조31례、동통1급조86례、동통2급조25례，장기MRI골수수종분위0급(무골수수종)38례、1급(경도골수수종)69례、2급(교대골수수종)35례，장동통정도여KOA골수수종분급진행χ2검험，병장동통각조여수종분급진행다개독립양본비교적질화검험。결과：무동통조29.1％(9/31례)존재BME，동통1급조82.6％(71/86례)존재BME，동통2급조92％(24/25례)존재BME；무동통조여동통1급조、동통2급조상비차이유통계학의의(χ2=12.613，P＜0.001；χ2=14.535，P＜0.001)，다개독립양본비교적질화검험현시，3조BME차이유통계학의의(P＜0.001)，수동통적가중，BME분급적평균질차축점가대(0급、1급화2급분별위79.12、102.82화139.26)。결론：KOA동통여연골하골수수종상관，차존재동통월중、골수수종월엄중적추세。
Objective To evaluate whether the presence of subchondral bone marrow edema(BME), detect?ed by magnetic resonance imaging(MRI), are associated with different levels of pain among patients suffering os?teoarthritis of the knee. Methods Based on rating scale of pain, 142 patients with knee osteoarthritis (OA) were divided into three groups: no pain group, 31; mild pain group, 86;moderate or severe pain group, 25. Con?tingency table analyses and rank sum tests were used to compare the difference among pain stages of OA and BME score in these groups. While BME was identified from MRI(0 grade,no BME,38;grade 1,small BME, 69;grade 2,large BME,35). Results 29.1%(9/31)of OA patients in no pain group had BME, while in mild pain group the percentage was 82.6%(71/86),in severe pain gmup 92%(24/25). There was statistical signifi?cance between no pain group and mild pain group(χ2=12.613,P<0.001);so was it between no pajn group and severe pain group(χ2=14.535,P<0.001). The results of rank sum tests for several independent samples showed significant differences of BME scoring among the three groups(P<0.001). With the advance of pain scale,the mean rank of BME increased gradually (79.12、102.82 and 139.26 respectively). Conclusion The finding on MRI of subchondral BME was associated with the presence or absence of knee pain.There seemed to be a ten?dency:the more heavier the pain was,the larger the BMEwould be.