北华大学学报(自然科学版)
北華大學學報(自然科學版)
북화대학학보(자연과학판)
JOURNAL OF BEIHUA UNIVERSITY(NATURAL SCIENCE)
2015年
4期
471-475
,共5页
刘楠楠%于春艳%董志恒%刘玉和%盖晓东%王丹
劉楠楠%于春豔%董誌恆%劉玉和%蓋曉東%王丹
류남남%우춘염%동지항%류옥화%개효동%왕단
系统性红斑狼疮%尸体解剖%狼疮性肾炎
繫統性紅斑狼瘡%尸體解剖%狼瘡性腎炎
계통성홍반랑창%시체해부%랑창성신염
systemic lupus erythematosus%autopsy%lupus nephritis
目的:探讨系统性红斑狼疮( systemic lupus erythematosus,SLE)的临床病理特点、死亡原因。方法对3例SLE尸检材料进行收集与整理,并对其临床资料与病理变化进行回顾性分析。结果 SLE可侵犯多个器官,以肾脏、心脏及皮肤为主。 SLE的病变主要表现为肾脏的狼疮性肾炎、心脏的非细菌性疣赘性心内膜炎与非细菌性纤维素性心外膜炎、皮肤面部的蝶形红斑。另一方面,3例SLE均伴有肺部的继发感染。结论 SLE可导致全身多个器官广泛病变,其临床表现与病理变化复杂多样。肾功能衰竭与肺部感染是SLE患者的死亡原因。
目的:探討繫統性紅斑狼瘡( systemic lupus erythematosus,SLE)的臨床病理特點、死亡原因。方法對3例SLE尸檢材料進行收集與整理,併對其臨床資料與病理變化進行迴顧性分析。結果 SLE可侵犯多箇器官,以腎髒、心髒及皮膚為主。 SLE的病變主要錶現為腎髒的狼瘡性腎炎、心髒的非細菌性疣贅性心內膜炎與非細菌性纖維素性心外膜炎、皮膚麵部的蝶形紅斑。另一方麵,3例SLE均伴有肺部的繼髮感染。結論 SLE可導緻全身多箇器官廣汎病變,其臨床錶現與病理變化複雜多樣。腎功能衰竭與肺部感染是SLE患者的死亡原因。
목적:탐토계통성홍반랑창( systemic lupus erythematosus,SLE)적림상병리특점、사망원인。방법대3례SLE시검재료진행수집여정리,병대기림상자료여병리변화진행회고성분석。결과 SLE가침범다개기관,이신장、심장급피부위주。 SLE적병변주요표현위신장적랑창성신염、심장적비세균성우췌성심내막염여비세균성섬유소성심외막염、피부면부적접형홍반。령일방면,3례SLE균반유폐부적계발감염。결론 SLE가도치전신다개기관엄범병변,기림상표현여병리변화복잡다양。신공능쇠갈여폐부감염시SLE환자적사망원인。
Objective To investigate the clinical and pathological characteristics of systemic lupus erythematosus ( SLE) ,and causes of death in patient with SLE. Method The medical records and autopsy results of 3 cases with SLE were collected and arranged and the clinical data and pathological changes were retrospectively analyzed. Results Almost organs showed different degrees of damage,especially in kidney,heart and skin. There were 3 cases of pulmonary infection. The lesions of SLE were mainly lupus nephritis in kidney, nonbacterial verrucous endocarditis and nobecterial fibrinous pericarditis in heart,and erythematous butterfly blush in skin. Conclusion SLE may lead different damages of many organs in human body. The changes of its clinical and pathological manifestation are complicated. Renal failure and pulmonary infection are common causes of death in patient with SLE.