CAJ | 학술논문

目的：探讨经尿道膀胱内电灼止血及透明质酸钠膀胱灌注治疗放射性膀胱炎出血的效果。方法：选择放疗术后急性膀胱出血患者60例，随机分为非手术组，经尿道膀胱内止血联合高压氧舱治疗组以及经尿道膀胱内止血联合透明质酸钠膀胱灌注组，观察疗效，采用尿道综合征症状评分表（FUSS）对患者相关症状进行评分。结果：经尿道止血+透明质酸钠膀胱灌注治疗放射性膀胱炎出血总有效率为95.0%，显著高于非手术组的70.0%和经尿道膀胱内止血-高压氧舱治疗组的80.0%（P＜0.05）；FUSS评分均显著高于保守治疗组和经尿道膀胱内止血联合高压氧舱治疗组（P＜0.05）；临床表现均显著优于治疗前（P＜0.05）。结论：经尿道膀胱内止血联合透明质酸钠膀胱灌注治疗放射性膀胱炎出血，操作简单，有效，实用。
목적：탐토경뇨도방광내전작지혈급투명질산납방광관주치료방사성방광염출혈적효과。방법：선택방료술후급성방광출혈환자60례，수궤분위비수술조，경뇨도방광내지혈연합고압양창치료조이급경뇨도방광내지혈연합투명질산납방광관주조，관찰료효，채용뇨도종합정증상평분표（FUSS）대환자상관증상진행평분。결과：경뇨도지혈+투명질산납방광관주치료방사성방광염출혈총유효솔위95.0%，현저고우비수술조적70.0%화경뇨도방광내지혈-고압양창치료조적80.0%（P＜0.05）；FUSS평분균현저고우보수치료조화경뇨도방광내지혈연합고압양창치료조（P＜0.05）；림상표현균현저우우치료전（P＜0.05）。결론：경뇨도방광내지혈연합투명질산납방광관주치료방사성방광염출혈，조작간단，유효，실용。
Objective To study clinical effect of electrocoagulation and sodium hyaluronate intravesical in?stillation in the treatment of hemorrhagic radiation cystitis. Methods Sixty patients with acute hemorrhage of bladder radiotherapy after surgery were randomly divided into 3 groups, 20 cases in each group; the conservative treatment group, transurethral resection of intra-bladder electrocoagulation+hyperbaric oxygen treatment group and electrocoagulation+sodium hyaluronate bladder reperfusion group. Urethral syndrome symptom score was used on the score sheet and related symptoms in patients with curative effect of the patients after treatment were observed. Results The total efficiency of transurethral hemostatic+sodium hyaluronate intravesical therapy of hemorrhagic radiation cystitis was 95%, significantly higher than those of the conservative treatment group (70%) and transurethral resection of the bladder in hemostatic+hyperbaric oxygen treatment group (80%), with statisti?cal significant difference, P<0.05;and transurethral hemostatic+sodium hyaluronate intravesical therapy of hem?orrhagic radiation cystitis FUSS scores were significantly higher than those in the conservative treatment group and transurethral resection of the bladder in hemostatic+hyperbaric oxygen treatment group, with statistically sig?nificant differences, P<0.05. And the use of transurethral resection of the bladder within the electrocoagulation and sodium hyaluronate intravesical therapy, patients in daytime and nighttime urination, urination urgency and urge incontinence were significantly better than those before treatment, with statistically significant differences, P<0.05. Conclusions Transurethral electrocoagulation+sodium hyaluronate intravesical therapy for hemor?rhagic radiation cystitis is a simple effective and practical operation, worthy for clinical promotion.