CAJ | 학술논문

目的：分析高频超声诊断早期类风湿关节炎的应用价值。方法以该院收治的40例早期类风湿关节炎（RA ）患者为观察组，另选择40例健康者作为对照组，分别采用高频超声和X线对两组对象进行影像学检查。对比分析两组的超声检查结果和高频超声与X线对观察组患者膝关节髌上囊积液、滑膜增生及骨侵蚀的阳性检出率，以及观察组患者的C‐反应蛋白（CRP）、红细胞沉降率（ESR）指标与超声检查相关指标的相关性。结果观察组患者膝关节髌上囊积液、滑膜增生、滑膜彩色血流、骨侵蚀高频超声检查的阳性率均高于对照组（P＜0．05）；观察组患者的动脉阻力指数小于对照组，股骨内髁及外髁软骨厚度较对照组薄（P＜0．05）。高频超声对观察组患者膝关节髌上囊积液、滑膜增生、骨侵蚀的阳性检出率均高于X线等检查结果（P＜0．05）。观察组患者膝关节髌上囊积液厚度、滑膜增生厚度、滑膜彩色血流分级与CRP、ESR均存在一定的相关性（P＜0．01）。结论高频超声能较好地反映早期RA患者的病变情况，且对各病变的检出率高于X线片，高频超声检查指标与CRP、ESR有一定的相关性。
목적：분석고빈초성진단조기류풍습관절염적응용개치。방법이해원수치적40례조기류풍습관절염（RA ）환자위관찰조，령선택40례건강자작위대조조，분별채용고빈초성화X선대량조대상진행영상학검사。대비분석량조적초성검사결과화고빈초성여X선대관찰조환자슬관절빈상낭적액、활막증생급골침식적양성검출솔，이급관찰조환자적C‐반응단백（CRP）、홍세포침강솔（ESR）지표여초성검사상관지표적상관성。결과관찰조환자슬관절빈상낭적액、활막증생、활막채색혈류、골침식고빈초성검사적양성솔균고우대조조（P＜0．05）；관찰조환자적동맥조력지수소우대조조，고골내과급외과연골후도교대조조박（P＜0．05）。고빈초성대관찰조환자슬관절빈상낭적액、활막증생、골침식적양성검출솔균고우X선등검사결과（P＜0．05）。관찰조환자슬관절빈상낭적액후도、활막증생후도、활막채색혈류분급여CRP、ESR균존재일정적상관성（P＜0．01）。결론고빈초성능교호지반영조기RA환자적병변정황，차대각병변적검출솔고우X선편，고빈초성검사지표여CRP、ESR유일정적상관성。
Objective To study the application value of high frequency ultrasound to the diagnosis of early rheumatoid arthri‐tis .Methods 40 cases were selected ,who were diagnosed with early rheumatoid arthritis ,as the RA group ,another 40 healthy per‐sons were selected as the normal control group .Objects in the 2 groups were examined with high frequency ultrasound and X‐ray . Comparison of the examination results was made ,at the same time ,the results of suprapatellar bursa effusion ,synovial hyperplasia and bone erosion of the positive detection rate in group RA from the analysis of high‐frequency ultrasound and X‐ray examination were also compared .In addition ,the relativity between the related index and ESR index and CRP index in group RA was also ana‐lysed .Results The suprapatellar bursa effusion ,synovial hyperplasia ,bone erosion of color flow rate and bone erosion of the posi‐tive detection rate were higher than those in normal control group(P<0 .05);Compared with the control group ,the artery resist‐ance index was less ,the femoral condyle and lateral condylar cartilage thickness of RA group increased more(P<0 .05) .High fre‐quency ultrasound positive detection rate suprapatellar bursa effusion ,synovial hyperplasia ,bone erosion in patients of group RA were higher than those of X‐ray(P<0 .05) .The knee joint suprapatellar bursa effusion ,synovial hyperplasia of synovial membrane thickenss ,the thickness of the color blood flow grade and CRP ,ESR of patients in RA group were correlated(P<0 .01) .Conclusion High frequency ultrasound can respond to the situation of early rheumatoid arthritis patients ,and the lesion detection rates are higher ,there is a certain correlation between ultrasonographic indexes and CRP ,ESR .