CAJ | 학술논문

目的：探讨血清γ-谷氨酰转肽酶（GGT）、碱性磷酸酶（ALP）、超敏 C 反应蛋白（hs-CRP）在高龄股骨粗隆骨折患者中的变化及临床意义。方法102例内固定手术治疗的高龄股骨粗隆间骨折患者纳入观察组，选择40例非骨折体检老年者纳入对照组，比较两组血清 GGT、ALP 及 hs-CRP 水平，并比较不同预后患者血清 GGT、ALP 及 hs-CRP 水平。结果观察组血清 GGT、ALP 及 hs-CRP 水平明显高于对照组，差异有统计学意义（P ＜0．05）；随访12月后，死亡患者22例，存活80例患者中有34例发生各类并发症，其中死亡组及并发症患者血清 GGT、ALP 及 hs-CRP水平均明显高于存活组及无并发症组，差异均有统计学意义（P ＜0．05）。结论高龄股骨粗隆骨折患者的血清GGT、ALP 及 hs-CRP 均明显升高，且检测水平血清 GGT、ALP 及 hs-CRP 水平对于预测高龄股骨粗隆骨折的预后具有重要意义。
목적：탐토혈청γ-곡안선전태매（GGT）、감성린산매（ALP）、초민 C 반응단백（hs-CRP）재고령고골조륭골절환자중적변화급림상의의。방법102례내고정수술치료적고령고골조륭간골절환자납입관찰조，선택40례비골절체검노년자납입대조조，비교량조혈청 GGT、ALP 급 hs-CRP 수평，병비교불동예후환자혈청 GGT、ALP 급 hs-CRP 수평。결과관찰조혈청 GGT、ALP 급 hs-CRP 수평명현고우대조조，차이유통계학의의（P ＜0．05）；수방12월후，사망환자22례，존활80례환자중유34례발생각류병발증，기중사망조급병발증환자혈청 GGT、ALP 급 hs-CRP수평균명현고우존활조급무병발증조，차이균유통계학의의（P ＜0．05）。결론고령고골조륭골절환자적혈청GGT、ALP 급 hs-CRP 균명현승고，차검측수평혈청 GGT、ALP 급 hs-CRP 수평대우예측고령고골조륭골절적예후구유중요의의。
Objective To investigate of clinical significance of combined serumγ-glutamyl endopeptidase(GGT),al-kaline phosphatase(ALP)with hs-CRP in aged patients with intertrochanteric fracture.Methods 102 aged patients with intertrochanteric fracture were included into the observation group,40 elderly people without fracture examination were included into the control group,the serum GGT,ALP and hs-CRP levels were compared,and those with different prognosis were compared.Results The serum GGT,ALP and hs-CRP levels in observation group were significantly higher than the control group (P <0.05);after follow-up of 12 months,there were of 22 patients died,34 patients with complications in 80 patients survived ,serum GGT,ALP and hs-CRP levels in death group and complication group were significantly higher than the survival group and non-complication group,the differences were of statistically significant (P <0.05).Conclusion The serum GGT,ALP and hs-CRP in aged patients with intertrochanteric fracture were signif-icantly higher,and the detection of these indicators is of great significance in predicting prognosis.