科技风
科技風
과기풍
TECHNOLOGY WIND
2015年
9期
2,9
,共2页
刘宁%李明春%马守栋
劉寧%李明春%馬守棟
류저%리명춘%마수동
Thermosensitive in situ gel of iodine%Dissolution%Release in vitro
objective:To Investigate the preparation, dissolution and release in vitro of thermosensitive in situ gel of iodine.Methods:Using orthogonal test method for screening the best prescription;Using the formula of gel accumulative dissolution percentage=(W1- Wt)/(W1- W0) to calculate the dissolution rate of Q by membrane- free; Calculating the accumulative release rate by the standard curve.As time increases, the dissolution rate and the release rate of the gel increased significantly. Conclusion: Thermosensitive in situ gel of iodine has good sustained release effect.