CAJ | 학술논문

目的：分析儿童 EB 病毒（EBV）感染的临床特点，提高对儿童 EBV 感染的认识。方法回顾性分析97例血清学诊断为 EBV 感染患儿的发病月份、年龄、临床表现，比较有无合并症两组间白细胞总数及其分类、CRP 等变化。结果EBV 感染患儿发病月份以春夏季最多（58例）；发病年龄以学龄前期最多（41例），其次为幼儿期（33例）、学龄期（20例）及婴儿期（3例）；EBV 感染临床表现以咽峡炎、发热、淋巴结肿大、肝脾大为最多；97例 EBV 感染患儿有合并症和无合并症两组间在白细胞总数、中性粒细胞比率、淋巴细胞比率及 CRP 值方面差异均无统计学意义（均 P ＞0．05）。结论1岁以内婴儿也可发生传染性单核细胞增多症，其临床表现具有多样性，可合并其他疾病，诊断应结合临床表现及实验室检查。
목적：분석인동 EB 병독（EBV）감염적림상특점，제고대인동 EBV 감염적인식。방법회고성분석97례혈청학진단위 EBV 감염환인적발병월빈、년령、림상표현，비교유무합병증량조간백세포총수급기분류、CRP 등변화。결과EBV 감염환인발병월빈이춘하계최다（58례）；발병년령이학령전기최다（41례），기차위유인기（33례）、학령기（20례）급영인기（3례）；EBV 감염림상표현이인협염、발열、림파결종대、간비대위최다；97례 EBV 감염환인유합병증화무합병증량조간재백세포총수、중성립세포비솔、림파세포비솔급 CRP 치방면차이균무통계학의의（균 P ＞0．05）。결론1세이내영인야가발생전염성단핵세포증다증，기림상표현구유다양성，가합병기타질병，진단응결합림상표현급실험실검사。
Objective To analyze the clinical characteristics of children infecting with Epstein -Barr virus. And in purpose to improve the knowledge of children infecting with Epstein -Barr virus.Methods We analyzed retrospectively to 97 cases of children which serodiagnosis of Epstein -Barr virus infectius in the aspects of the onset season,the age,clinical characteristics.And compared with complication group and no complication group in the aspects of the white cell count,neutrophils to white cell count ratio,lymphocyte to white cell count ratio and C -reactive protein.And contrasted the presence of statistical difference.Results The peak months were spring and summer(58 cases);Pre -school age was the peak age of EBV infectious(41 cases),and the rest respectively were toddlers age(33 cases),school age and youth(20 cases)and infant period(3 cases).The most frequently clinical manifestation respectively was pharyngitis,and other such as fever,lymphadenopathy,hepatosplenomegaly.There had no statistical difference in the two groups of complication group and no complication group in the aspects of the white cell count,neutrophils to white cell count ratio,lymphocyte to white cell count ratio and C -reactive protein(P >0.05).Conclusion The infant can suffer from infectious mononucleosis infect with EBV.Infectious mononucleosis have a variety of clinical manifestation,which always have some complications.The diognosis should combinate clini-cal manifestation with laberatory test.