CAJ | 학술논문

目的：调查并分析南京地区缺血性脑卒中二级预防中的危险因素。方法现将2013年03月～2013年12月在南京脑科医院门诊就诊的有过脑梗死（ CI ）病史或期间有CI发病的患者886例（ CI组）和头颅MRI显示仅有腔隙性脑梗死（ LI）病灶但无卒中发作史的患者1247例（ LI组）进行资料采集，包括性别、年龄、吸烟史、高血压、糖尿病、房颤史、心肌梗死史、外周动脉疾病、颅内外动脉狭窄情况及Essen卒中风险评分量表（ ESRS）。同时收集南京汤山社区和南湖社区缺血性脑卒中中低危人群9739例（ LR组）的相关数据，对三组数据进行分析比较。结果 CI组和LI组高血压、糖尿病比率显著高于LR组（均P＜0．01）。 CI组颅内外动脉狭窄比率显著高于LI组（ P＜0．01）。进一步将脑梗死的六个危险因素进行多元Logistic回归分析结果均无统计学意义。 CI组与LI组ESRS风险分级比例之间比较无统计学差异。结论南京地区高血压、糖尿病是CI的常见危险因素。在缺血性脑卒中的危险因素中对颅内外动脉狭窄的监测更为重要。
목적：조사병분석남경지구결혈성뇌졸중이급예방중적위험인소。방법현장2013년03월～2013년12월재남경뇌과의원문진취진적유과뇌경사（ CI ）병사혹기간유CI발병적환자886례（ CI조）화두로MRI현시부유강극성뇌경사（ LI）병조단무졸중발작사적환자1247례（ LI조）진행자료채집，포괄성별、년령、흡연사、고혈압、당뇨병、방전사、심기경사사、외주동맥질병、로내외동맥협착정황급Essen졸중풍험평분량표（ ESRS）。동시수집남경탕산사구화남호사구결혈성뇌졸중중저위인군9739례（ LR조）적상관수거，대삼조수거진행분석비교。결과 CI조화LI조고혈압、당뇨병비솔현저고우LR조（균P＜0．01）。 CI조로내외동맥협착비솔현저고우LI조（ P＜0．01）。진일보장뇌경사적륙개위험인소진행다원Logistic회귀분석결과균무통계학의의。 CI조여LI조ESRS풍험분급비례지간비교무통계학차이。결론남경지구고혈압、당뇨병시CI적상견위험인소。재결혈성뇌졸중적위험인소중대로내외동맥협착적감측경위중요。
Objective To investigate the risk factors of ischemic stroke in secondary prevention in Nanjing area.Methods The data of 886 patients in clinics of Nanjing Brain Hospital from March 2013 to December 2013 who had history of cerebral infarction ( CI ) or had CI outbreak ( CI group ) and 1247 patients who had only lacunar infarction (LI) lesions but no stroke history(LI group) were registered, including sex, age, smoking, hypertension, diabetes, atrial fibrillation,myocardial infarction, peripheral arterial disease, intracranial and extracranial artery stenosis,Essen score.Also, the related data of low risk population in 9739 cases ( LR group) of Nanjing Tangshan and Nanhu community were collected , and risk factors of the three groups were compared .Results The risk rates of diabetes and hypertension in CI group and LI group were significantly higher than those in LR group (all P<0.01). The rate of intracranial and extracranial artery stenosis in CI group was significantly higher than that in LI group ( P<0.01).There were no significant differences in muti-logistic regression of six risk factors of cerebral infarction .And there were no significant differences in ESRS between CI group and LI group .Conclusions Hypertension and diabetes are the common risk factors of CI in Nanjing area .The monitoring of intracranial and extracranial artery stenosis was more important in these risk factors for ischemic stroke .