临床神经病学杂志
臨床神經病學雜誌
림상신경병학잡지
JOURNAL OF CLINICAL NEUROLOGY
2015年
3期
172-176
,共5页
吕利英%国钰梅%黄泽宇%杨丽荣%包成月%白文婷%程慧%李方睿%金星灿%佟伟军%周蓦%许锬
呂利英%國鈺梅%黃澤宇%楊麗榮%包成月%白文婷%程慧%李方睿%金星燦%佟偉軍%週驀%許錟
려리영%국옥매%황택우%양려영%포성월%백문정%정혜%리방예%금성찬%동위군%주맥%허담
急性缺血性脑卒中%白细胞%出院结局
急性缺血性腦卒中%白細胞%齣院結跼
급성결혈성뇌졸중%백세포%출원결국
acute ischemic stroke%white blood cell%discharged outcome
目的:探讨缺血性脑卒中患者入院时不同白细胞水平与出院结局的关系。方法连续性纳入内蒙古兴安盟人民医院2009年6月1日~2012年5月31日的全部缺血性脑卒中患者为研究对象,共计3440例,分析入院时白细胞水平与急性缺血性脑卒中患者出院结局的关系。结果研究对象中发生不良结局的共有359人,占10.44%。单因素Logistic回归分析显示,年龄、体温、高血压、高血糖、脑卒中病史和吸烟、饮酒是发生结局不良的危险因素(均P<0.01),高三酰甘油是发生结局不良的保护因素(P<0.01)。与白细胞计数最低分位组相比,第3、4分位组结局不良明显增多( OR=1.78,95%CI:1.23~2.58;OR=3.98,95%CI:2.85~5.56;均P<0.001)。在调整了年龄,体温,高血压,高血糖,脑卒中病史,高甘油三酯,吸烟和饮酒后,与白细胞计数最低分位组相比,第3、4分位组结局不良明显增多( OR=1.77,95%CI:1.20~2.61;OR=3.76,95%CI:2.63~5.37;均P<0.001)。结论急性缺血性脑卒中患者入院时较高的白细胞水平可能是出院结局不良的独立危险因素。
目的:探討缺血性腦卒中患者入院時不同白細胞水平與齣院結跼的關繫。方法連續性納入內矇古興安盟人民醫院2009年6月1日~2012年5月31日的全部缺血性腦卒中患者為研究對象,共計3440例,分析入院時白細胞水平與急性缺血性腦卒中患者齣院結跼的關繫。結果研究對象中髮生不良結跼的共有359人,佔10.44%。單因素Logistic迴歸分析顯示,年齡、體溫、高血壓、高血糖、腦卒中病史和吸煙、飲酒是髮生結跼不良的危險因素(均P<0.01),高三酰甘油是髮生結跼不良的保護因素(P<0.01)。與白細胞計數最低分位組相比,第3、4分位組結跼不良明顯增多( OR=1.78,95%CI:1.23~2.58;OR=3.98,95%CI:2.85~5.56;均P<0.001)。在調整瞭年齡,體溫,高血壓,高血糖,腦卒中病史,高甘油三酯,吸煙和飲酒後,與白細胞計數最低分位組相比,第3、4分位組結跼不良明顯增多( OR=1.77,95%CI:1.20~2.61;OR=3.76,95%CI:2.63~5.37;均P<0.001)。結論急性缺血性腦卒中患者入院時較高的白細胞水平可能是齣院結跼不良的獨立危險因素。
목적:탐토결혈성뇌졸중환자입원시불동백세포수평여출원결국적관계。방법련속성납입내몽고흥안맹인민의원2009년6월1일~2012년5월31일적전부결혈성뇌졸중환자위연구대상,공계3440례,분석입원시백세포수평여급성결혈성뇌졸중환자출원결국적관계。결과연구대상중발생불량결국적공유359인,점10.44%。단인소Logistic회귀분석현시,년령、체온、고혈압、고혈당、뇌졸중병사화흡연、음주시발생결국불량적위험인소(균P<0.01),고삼선감유시발생결국불량적보호인소(P<0.01)。여백세포계수최저분위조상비,제3、4분위조결국불량명현증다( OR=1.78,95%CI:1.23~2.58;OR=3.98,95%CI:2.85~5.56;균P<0.001)。재조정료년령,체온,고혈압,고혈당,뇌졸중병사,고감유삼지,흡연화음주후,여백세포계수최저분위조상비,제3、4분위조결국불량명현증다( OR=1.77,95%CI:1.20~2.61;OR=3.76,95%CI:2.63~5.37;균P<0.001)。결론급성결혈성뇌졸중환자입원시교고적백세포수평가능시출원결국불량적독립위험인소。
Objective To discuss the association between different white blood cell levels of patients at admission and discharged outcome of acute ischemic stroke patients .Methods The patients with acute ischemic stroke in Xing'anmeng People's Hospital from June 1, 2009 to May 31, 2012 were collected, adding up to 3 440 consecutive cases , analyzed the relationship between white blood cell levels at admission and discharge outcome in patients with acute ischemic stroke .Results A total of 359 people occurred poor outcomes in the study , accounting for 10.44%.Univariate Logistic regression analysis showed that age , body temperature,hypertension, high blood sugar,history of stroke and smoking, drinking were the risk factors of adverse outcomes ( all P<0.01), high triglyceride was the protective factors of adverse outcome ( P<0.01) .Compared with the lowest quartile group of white blood cell count, the third and fourth quartile groups had significantly more poor outcomes (OR=1.78,95%CI:1.23-2.58;OR =3.98,95%CI:2.85 -5.56;all P<0.001).After adjusting age, body temperature, blood pressure, high blood sugar, history of stroke, high triglycerides, smoking and drinking,compared with the lowest quartile group of white blood cell count , the third and fourth quartile groups had significantly more poor outcomes (OR=1.77,95%CI:1.20-2.61;OR=3.76,95%CI:2.63-5.37;all P<0.001).Conclusion Higher levels of white blood cell may be the independent risk factor for poor discharged outcome in patients with acute ischemic stroke.