风湿病与关节炎
風濕病與關節炎
풍습병여관절염
Rheumatism and Arthritis
2015年
6期
13-15,23
,共4页
腰椎间盘突出症%寒湿型%杨氏萆薢分清饮%桂枝加葛根汤%炎性疼痛
腰椎間盤突齣癥%寒濕型%楊氏萆薢分清飲%桂枝加葛根湯%炎性疼痛
요추간반돌출증%한습형%양씨비해분청음%계지가갈근탕%염성동통
lumbar disc herniation%cold-dampness type%Yang's Bixie Fenqing Drink(杨氏萆薢分清饮)%Guizhi Jia Gegen Decoction(桂枝加葛根汤)%inlfammatory pain
目的:观察杨氏萆薢分清饮和桂枝加葛根汤加减治疗寒湿型腰椎间盘突出症的临床疗效。方法:将90例寒湿型腰椎间盘突出症患者随机分为治疗组和对照组,每组45例。治疗组给予杨氏萆薢分清饮和桂枝加葛根汤加减治疗,对照组给予双氯芬酸钠缓释片口服治疗。两组均以20 d为1个疗程,1个疗程及随访6个月后,评定患者临床疗效、安全性指标及远期疗效,并进行统计学分析。结果:1个疗程后,治疗组显效30例,有效12例,无效3例,总有效率为93.33%;对照组显效28例,有效13例,无效4例,总有效率为91.11%。两组比较,差异无统计学意义(P >0.05)。治疗组无不良反应发生;对照组发生不良反应7例,其中胃肠道不适5例,肝功能损害1例,皮疹1例,停药后自行好转。两组不良反应比较,差异有统计学意义(P <0.05),治疗组较对照组安全性高。随访6个月,治疗组显效29例,有效11例,无效5例,总有效率为88.89%;对照组显效22例,有效9例,无效14例,总有效率为68.89%。两组比较,差异有统计学意义(P <0.05)。结论:采用杨氏萆薢分清饮和桂枝加葛根汤加减治疗寒湿型腰椎间盘突出症,临床疗效满意,安全性较好,且远期疗效可观,值得在临床推广应用。
目的:觀察楊氏萆薢分清飲和桂枝加葛根湯加減治療寒濕型腰椎間盤突齣癥的臨床療效。方法:將90例寒濕型腰椎間盤突齣癥患者隨機分為治療組和對照組,每組45例。治療組給予楊氏萆薢分清飲和桂枝加葛根湯加減治療,對照組給予雙氯芬痠鈉緩釋片口服治療。兩組均以20 d為1箇療程,1箇療程及隨訪6箇月後,評定患者臨床療效、安全性指標及遠期療效,併進行統計學分析。結果:1箇療程後,治療組顯效30例,有效12例,無效3例,總有效率為93.33%;對照組顯效28例,有效13例,無效4例,總有效率為91.11%。兩組比較,差異無統計學意義(P >0.05)。治療組無不良反應髮生;對照組髮生不良反應7例,其中胃腸道不適5例,肝功能損害1例,皮疹1例,停藥後自行好轉。兩組不良反應比較,差異有統計學意義(P <0.05),治療組較對照組安全性高。隨訪6箇月,治療組顯效29例,有效11例,無效5例,總有效率為88.89%;對照組顯效22例,有效9例,無效14例,總有效率為68.89%。兩組比較,差異有統計學意義(P <0.05)。結論:採用楊氏萆薢分清飲和桂枝加葛根湯加減治療寒濕型腰椎間盤突齣癥,臨床療效滿意,安全性較好,且遠期療效可觀,值得在臨床推廣應用。
목적:관찰양씨비해분청음화계지가갈근탕가감치료한습형요추간반돌출증적림상료효。방법:장90례한습형요추간반돌출증환자수궤분위치료조화대조조,매조45례。치료조급여양씨비해분청음화계지가갈근탕가감치료,대조조급여쌍록분산납완석편구복치료。량조균이20 d위1개료정,1개료정급수방6개월후,평정환자림상료효、안전성지표급원기료효,병진행통계학분석。결과:1개료정후,치료조현효30례,유효12례,무효3례,총유효솔위93.33%;대조조현효28례,유효13례,무효4례,총유효솔위91.11%。량조비교,차이무통계학의의(P >0.05)。치료조무불량반응발생;대조조발생불량반응7례,기중위장도불괄5례,간공능손해1례,피진1례,정약후자행호전。량조불량반응비교,차이유통계학의의(P <0.05),치료조교대조조안전성고。수방6개월,치료조현효29례,유효11례,무효5례,총유효솔위88.89%;대조조현효22례,유효9례,무효14례,총유효솔위68.89%。량조비교,차이유통계학의의(P <0.05)。결론:채용양씨비해분청음화계지가갈근탕가감치료한습형요추간반돌출증,림상료효만의,안전성교호,차원기료효가관,치득재림상추엄응용。
[ABSTRACT]Objective:To observe the clinical curative effect of Yang's Bixie Fenqing Drink(杨氏萆薢分清饮)and Guizhi Jia Gegen Decoction(桂枝加葛根汤)in the treatment of cold-dampness-type lumbar disc herniation.Methods:90 cases of cold-dampness-type lumbar disc herniation were randomly divided into a treatment group and a control group,45 cases in each group.The treatment group were treated with Yang's Bixie Fenqing Drink and Guizhi Jia Gegen Decoction,while the control group were treated with diclofenac sodium sustained-release tablets.20 days was a course of treatment.After 1 course and 6-month follow-up,the clinical efficacy,safety index and the long-term curative effect were evaluated,and the statistical analysis was carried out.Results:After 1 course,in the treatment group,30 cases were excellent,12 cases were effective,and 3 cases were ineffective,the total effective rate being 93.33%;in the control group,28 cases were excellent,13 cases were effective,and 4 cases were ineffective,the total effective rate being 91.11%.There was no signiifcant difference between the two groups(P >0.05).There were no adverse reactions in the treatment group,while there were 7 cases in the control group having adverse reaction,5 cases with gastrointestinal discomfort,1 case with liver function damage,and 1 case with rash,getting better after stopping the drug.The differences of adverse reactions inthe two groups were statistically signiifcant (P <0.05),and the treatment group was more safe than the control group.After 6-month follow up,in the treatment group,29 cases were markedly effective,11 cases were effective,and 5 cases were invalid,the total effective rate being 88.89%;while in the control group,22 cases were markedly effective, 9 cases were effective,and 14 cases were invalid,the total effective rate being 68.89%.The difference between the two groups was statistically signiifcant (P <0.05).Conclusion:Yang's Bixie Fenqing Drink and Guizhi Jia Gegen Decoction are effective and safe in the treatment of cold-dampness-type lumbar disc herniation,worthy of being clinically applied.