CAJ | 학술논문

目的：分析自发脑出血患者血浆高敏C反应蛋白（hs‐CRP）的变化与病情的关系。方法分析我科2009－2012年收治的自发脑出血64例患者，均无外伤病史，所有患者入院1～2 d内查高敏C反应蛋白。结果高血压脑出血47例，非高血压性脑出血17例[hs‐CRP（18.78±22.76） mg／L vs （6.85±8.32） mg／L ，P＝0.0036]；高血压中手术者10例，非手术者37例[hs‐CRP（47.52±28.32） mg／L vs （11.01±12.55） mg／L ，P＝0.0037]。结论高血压脑出血患者血浆hs‐CRP值明显高于非高血压脑出血，且与患者病情严重程度相关，手术组血浆hs‐CRP值明显高于非手术组，说明血浆hs‐CRP可作为判断患者病情严重程度及预后监测指标之一。
목적：분석자발뇌출혈환자혈장고민C반응단백（hs‐CRP）적변화여병정적관계。방법분석아과2009－2012년수치적자발뇌출혈64례환자，균무외상병사，소유환자입원1～2 d내사고민C반응단백。결과고혈압뇌출혈47례，비고혈압성뇌출혈17례[hs‐CRP（18.78±22.76） mg／L vs （6.85±8.32） mg／L ，P＝0.0036]；고혈압중수술자10례，비수술자37례[hs‐CRP（47.52±28.32） mg／L vs （11.01±12.55） mg／L ，P＝0.0037]。결론고혈압뇌출혈환자혈장hs‐CRP치명현고우비고혈압뇌출혈，차여환자병정엄중정도상관，수술조혈장hs‐CRP치명현고우비수술조，설명혈장hs‐CRP가작위판단환자병정엄중정도급예후감측지표지일。
Objective To analyze the relationship between the changes of plasma high sensitive C‐reaction protein (hs‐CRP) and disease in spontaneous intracerebral hemorrhage patients.Methods Total of 64 cases with spontaneous intracerebral hemorrhage in our department from 2009 to 2012 were analyzed ,all patients had no history of trauma ,hs‐CRP was detected within 2‐day hospital admission.Results There were 47 cases with hypertensive hemorrhage(hs‐CRP (18 .78 ± 22 .76) mg /L) and 17cases with non‐hypertensive hemorrhage(hs‐CRP (11 .01 ± 12 .55) mg/L) ,the difference showed no statistical signifi‐cance(P=0 .0036);Among hypertensive intracerebral hemorrhage cases ,10 cases operated(hs‐CRP (47 .52 ± 28 .32) mg/L) , 37 cases had no operation((11 .01 ± 12 .55) mg/L) ,with the statistical difference(P=0 .0037).Conclusion The value of plas‐ma hs‐CRP in patients with hypertensive intracerebral hemorrhage is significantly higher than that of non‐hypertensive intrace‐rebral hemorrhage ,which is related to the severity degree of condition.The value of plasma hs‐CRP in operation group is signif‐icantly higher than that of non‐operation group.So the plasma hs‐CRP can be used as one of severity and prognosis indexes .