临床与病理杂志
臨床與病理雜誌
림상여병리잡지
International Journal of Pathology and Clinical Medicine
2015年
6期
1052-1056
,共5页
开角型青光眼%糖尿病%小梁切除术%脉络膜
開角型青光眼%糖尿病%小樑切除術%脈絡膜
개각형청광안%당뇨병%소량절제술%맥락막
open-angle glaucoma%diabetes mellitus%trabeculectomy%choroid
目的：观察开角型青光眼(primary open angle glaucoma，POAG)与开角型青光眼合并糖尿病患者小梁切除术后脉络膜厚度的变化。方法：选择在我院眼科住院治疗的开角型青光眼患者120例(130只眼)为研究对象，根据是否合并有糖尿病分为青光眼组69例(76只眼)和合并糖尿病组51例(54只眼)，应用光学相干断层扫描技术(optical coherence tomography，OCT)于小梁切除术前后对视网膜色素上皮层到内巩膜层的垂直距离(即脉络膜厚度)进行测量。通过软件计算自动获得脉络膜平均厚度，观察并与术前比较是否有改变。结果：术前，两组视力、眼压和脉络膜厚度均无统计学差异(P>0.05)。小梁切除术后2周，合并糖尿病组脉络膜厚度比青光眼组厚，两组比较，差异具有统计学意义(P<0.05)；但两组视力与眼压均无统计学差异(P>0.05)。组内治疗前后情况，两组视力与脉络膜厚度无统计学差异(P>0.05)，但眼压在术后明显降低，差异具有统计学意义(t=10.76，P=0.00)。结论：开角型青光眼是否合并有糖尿病于小梁切除术后对脉络膜厚度无影响。
目的：觀察開角型青光眼(primary open angle glaucoma，POAG)與開角型青光眼閤併糖尿病患者小樑切除術後脈絡膜厚度的變化。方法：選擇在我院眼科住院治療的開角型青光眼患者120例(130隻眼)為研究對象，根據是否閤併有糖尿病分為青光眼組69例(76隻眼)和閤併糖尿病組51例(54隻眼)，應用光學相榦斷層掃描技術(optical coherence tomography，OCT)于小樑切除術前後對視網膜色素上皮層到內鞏膜層的垂直距離(即脈絡膜厚度)進行測量。通過軟件計算自動穫得脈絡膜平均厚度，觀察併與術前比較是否有改變。結果：術前，兩組視力、眼壓和脈絡膜厚度均無統計學差異(P>0.05)。小樑切除術後2週，閤併糖尿病組脈絡膜厚度比青光眼組厚，兩組比較，差異具有統計學意義(P<0.05)；但兩組視力與眼壓均無統計學差異(P>0.05)。組內治療前後情況，兩組視力與脈絡膜厚度無統計學差異(P>0.05)，但眼壓在術後明顯降低，差異具有統計學意義(t=10.76，P=0.00)。結論：開角型青光眼是否閤併有糖尿病于小樑切除術後對脈絡膜厚度無影響。
목적：관찰개각형청광안(primary open angle glaucoma，POAG)여개각형청광안합병당뇨병환자소량절제술후맥락막후도적변화。방법：선택재아원안과주원치료적개각형청광안환자120례(130지안)위연구대상，근거시부합병유당뇨병분위청광안조69례(76지안)화합병당뇨병조51례(54지안)，응용광학상간단층소묘기술(optical coherence tomography，OCT)우소량절제술전후대시망막색소상피층도내공막층적수직거리(즉맥락막후도)진행측량。통과연건계산자동획득맥락막평균후도，관찰병여술전비교시부유개변。결과：술전，량조시력、안압화맥락막후도균무통계학차이(P>0.05)。소량절제술후2주，합병당뇨병조맥락막후도비청광안조후，량조비교，차이구유통계학의의(P<0.05)；단량조시력여안압균무통계학차이(P>0.05)。조내치료전후정황，량조시력여맥락막후도무통계학차이(P>0.05)，단안압재술후명현강저，차이구유통계학의의(t=10.76，P=0.00)。결론：개각형청광안시부합병유당뇨병우소량절제술후대맥락막후도무영향。
Objective:Observe on the changes of choroidal thickness after trabeculectomy in the open-angle glaucoma (POAG) patients and the open-angle glaucoma also suffering diabetes patients.Methods:A total of 120 POAG patients (130 eyes) whom were therapied in our hospital were chose in this study. hTe subjects were divided into glaucoma groups (69 cases, 76 eyes) and diabetes group (51 cases, 54 eyes) according to whether merge diabetes. Measure the vertical distance between the retinal pigment epithelium and the scleral layer with OCT. hTe average choroidal thickness is calculated automatically by the sotfware. hTe changes were observed and compared with the preoperative.Results: Preoperatively the differences of the visual acuity, intraocular pressure and choroidalthickness of the two groups were no statistically significant (P>0.05). Two weeks after trabeculectomy, the choroidal thickness of the diabetic group was thicker than the glaucoma group. hTe difference between the two groups were statistically signiifcant (P<0.05). But the differences of the visual acuity and intraocular pressure were no statistically signiifcant (P>0.05). hTe situation within the group before and atfer treatment, the differences of visual acuity and choroidal thickness were no statistically signiifcant (P>0.05), but the intraocular pressure was decreased significantly after surgery, which was statistically significant (t=10.76,P=0.00).Conclusion: Open-angle glaucoma whether merge diabetes does not affect the thickness of the choroid atfer trabeculectomy.
