中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
EVALUATION AND ANAL YSIS OF DRUG-USE IN HOSPITALS OF CHINA
2015年
6期
732-734
,共3页
肺肿瘤/中医药疗法%药物疗法%益气化瘀法
肺腫瘤/中醫藥療法%藥物療法%益氣化瘀法
폐종류/중의약요법%약물요법%익기화어법
Lung neoplasms/TCM therapy%Drug therapy%Method of supplementing Qi and removing blood stasis
目的：探讨晚期肺癌患者应用益气化瘀法配合化疗治疗效果。方法：本组79例患者根据随机数字表法随机分为观察组（n＝42）和对照组（n＝37）。观察组采用益气化瘀法联合化疗治疗，对照组单用化疗方案治疗。对比分析治疗前后2组疗效、生活质量评价、免疫功能指标水平变化等。结果：观察组患者的总有效率（54．76％，23／42）显著高于对照组（32．43％，12／37），差异有统计学意义（ P＜0．05）；观察组卡氏评分提高率显著高于对照组，而降低率显著低于对照组，差异均具有统计学意义（ P＜0．05）；观察组CD3＋、CD4＋、CD4＋／CD8＋显著低于对照组，CD8＋显著高于对照组，差异均具有统计学意义（ P＜0．05）。结论：晚期肺癌患者应用益气化瘀法配合化疗效果显著，具有重要临床意义。
目的：探討晚期肺癌患者應用益氣化瘀法配閤化療治療效果。方法：本組79例患者根據隨機數字錶法隨機分為觀察組（n＝42）和對照組（n＝37）。觀察組採用益氣化瘀法聯閤化療治療，對照組單用化療方案治療。對比分析治療前後2組療效、生活質量評價、免疫功能指標水平變化等。結果：觀察組患者的總有效率（54．76％，23／42）顯著高于對照組（32．43％，12／37），差異有統計學意義（ P＜0．05）；觀察組卡氏評分提高率顯著高于對照組，而降低率顯著低于對照組，差異均具有統計學意義（ P＜0．05）；觀察組CD3＋、CD4＋、CD4＋／CD8＋顯著低于對照組，CD8＋顯著高于對照組，差異均具有統計學意義（ P＜0．05）。結論：晚期肺癌患者應用益氣化瘀法配閤化療效果顯著，具有重要臨床意義。
목적：탐토만기폐암환자응용익기화어법배합화료치료효과。방법：본조79례환자근거수궤수자표법수궤분위관찰조（n＝42）화대조조（n＝37）。관찰조채용익기화어법연합화료치료，대조조단용화료방안치료。대비분석치료전후2조료효、생활질량평개、면역공능지표수평변화등。결과：관찰조환자적총유효솔（54．76％，23／42）현저고우대조조（32．43％，12／37），차이유통계학의의（ P＜0．05）；관찰조잡씨평분제고솔현저고우대조조，이강저솔현저저우대조조，차이균구유통계학의의（ P＜0．05）；관찰조CD3＋、CD4＋、CD4＋／CD8＋현저저우대조조，CD8＋현저고우대조조，차이균구유통계학의의（ P＜0．05）。결론：만기폐암환자응용익기화어법배합화료효과현저，구유중요림상의의。
OBJECTIVE:To investigate the efficacy of Tonifying Qi and Removing Blood Stasis Therapy plus chemotherapy for advanced lung cancer.METHODS:79 patients with advanced lung cancer were randomly assigned to either observation group ( n=42 ) treated with tonifying Qi and removing blood stasis therapy plus chemotherapy or control group (n=37) treated with chemotherapy alone.The treatment efficacy, the quality of life, and the level of immune indicators in the two groups were followed.RESULTS:The total response rate was significantly higher in the observation group than in the control group [47.62%(23/42) vs.32.43%(12/37), P<0.05]; the proportion of patients showing KPS score increase in the observation group was significantly higher than in the control group, yet the proportion of patients showing KPS score decrease in the observation group was significantly lower than in the control group ( P<0.05 ); the levels of CD3 +, CD4 +, CD4 +/CD8 + were significantly lower while the CD8 +level was significantly higher in the observation group than in the control group ( P<0.05 ) .CONCLUSIONS:The application of tonifying Qi and removing blood stasis therapy plus chemotherapy for advanced lung cancer achieved remarkable efficacy, which thus is of great clinical significance.
