CAJ | 학술논문

以贺兰山紫蘑菇为材料，研究石油醚、乙酸乙酯、正丁醇萃取物和水提物对乳腺癌231细胞的抑制效果，通过乙醇浸提以及有机溶剂萃取等步骤得到各有机相后，采用MTT法筛选各相萃取物抗肿瘤活性。结果表明：贺兰山紫蘑菇石油醚、乙酸乙酯、正丁醇萃取物对乳腺癌231细胞均有抑制作用，石油醚萃取物效果最佳，在浓度为0.225 mg／mL时抑制率可达96.99％。而水相提取物对癌细胞抑制作用较弱。
이하란산자마고위재료，연구석유미、을산을지、정정순췌취물화수제물대유선암231세포적억제효과，통과을순침제이급유궤용제췌취등보취득도각유궤상후，채용MTT법사선각상췌취물항종류활성。결과표명：하란산자마고석유미、을산을지、정정순췌취물대유선암231세포균유억제작용，석유미췌취물효과최가，재농도위0.225 mg／mL시억제솔가체96.99％。이수상제취물대암세포억제작용교약。
Taking Cortinarius rufo-olivaceus as materials , the inhibitory effect of petroleum ether , ethyl acetate , n-butanol extract and water extract on 231 breast cancer cells was studied.Obtained the organic phase by ethanol extraction and organic solvent extraction steps , anti-tumor activity of each phase of extracts extracted by MTT method was screened.The result showed that Cortinarius rufo-olivaceus petroleum ether , ethyl acetate and n-butanol extracts on 231 breast cancer cells had inhibitory effect , the petroleum ether extract had the best effect , inhibition rate was up to 96.99%when the concentration was 0.225 mg/mL, but the water extract had weaker inhibition of cancer cell.