CAJ | 학술논문

微循环功能障碍参与了糖尿病及其并发症的发病机制,其机制包括胰岛微循环功能异常影响胰岛β细胞的生理功能、微血管自律运动功能受损导致外周肌肉组织胰岛素抵抗、靶器官微循环功能障碍引起的靶细胞进行性损伤等.
미순배공능장애삼여료당뇨병급기병발증적발병궤제,기궤제포괄이도미순배공능이상영향이도β세포적생리공능、미혈관자률운동공능수손도치외주기육조직이도소저항、파기관미순배공능장애인기적파세포진행성손상등.
Microcirculation dysfunction is involved in the onset of diabetes and its complications.The pathophysiological mechanisms behind the relationship between microcirculation and diabetes are multifactorial.Islet microcirculation dysfunction affects function of islet β cells.Impairment of microvascular vasomotion might be associated with insulin resistance.Microcirculation dysfunction of target organs mediates diabetic complications.