CAJ | 학술논문

目的：探讨改进冲管方法对用于输注两性霉素 B 的 PICC 管路的影响。方法以时间为顺序进行便利抽样分组，将2011年1月—2013年1月收治的采用两性霉素 B 治疗的20例患者作为对照组，将2013年2月—2014年6月收治的15例患者作为研究组。对照组采用常规方法冲管，即输注两性霉素 B 前后使用5%葡萄糖注射液静点冲管；研究组采用改良方法冲管，即在常规方法冲管后加用5%葡萄糖注射液10 ml 脉冲式冲管。比较两组患者 PICC 单次置管留置时间及药物堵塞性非计划拔管率。结果对照组患者 PICC 单次置管留置时间为（30.5±15.3）d，研究组为（97.5±35.9）d，差异有统计学意义（t =-6.785，P ＜0.01）；对照组药物堵塞性非计划拔管率为80.0%，研究组为6.7%，差异有统计学意义（χ2=18.453，P ＜0.01）。结论改良冲管法可以有效延长 PICC 单次置管留置时间并降低药物堵塞性非计划拔管率。
목적：탐토개진충관방법대용우수주량성매소 B 적 PICC 관로적영향。방법이시간위순서진행편리추양분조，장2011년1월—2013년1월수치적채용량성매소 B 치료적20례환자작위대조조，장2013년2월—2014년6월수치적15례환자작위연구조。대조조채용상규방법충관，즉수주량성매소 B 전후사용5%포도당주사액정점충관；연구조채용개량방법충관，즉재상규방법충관후가용5%포도당주사액10 ml 맥충식충관。비교량조환자 PICC 단차치관류치시간급약물도새성비계화발관솔。결과대조조환자 PICC 단차치관류치시간위（30.5±15.3）d，연구조위（97.5±35.9）d，차이유통계학의의（t =-6.785，P ＜0.01）；대조조약물도새성비계화발관솔위80.0%，연구조위6.7%，차이유통계학의의（χ2=18.453，P ＜0.01）。결론개량충관법가이유효연장 PICC 단차치관류치시간병강저약물도새성비계화발관솔。
Objective To discuss the impact on PICC infusion amphotericin B by improved flushing method. Methods A total of 20 patients with the treatment of amphotericin B were chosen as control group by convenience sampling method of time sequence from January 2011 to January 2013,while 15 patients with the treatment of amphotericin B were selected as experimental group from February 2013 to June 2014. The patients of control group underwent impulsive type flushing pipe with 5% glucose injection 10 ml before amphotericin B infusion,while the patients of experimental group received improved flushing method. We compared the length of PICC catheter indwelling time and rate of unplanned extubation caused by drug blocking. Results The length of PICC catheter indwelling time were(30. 5 ± 15. 3)days in the control group and(97. 5 ± 35. 9)days in the experimental group(t = -6.785,P <0.01);the rate of unplanned extubation because of drug blocking were 80.0%in the control group and 6.7% in the experimental group(χ2 =18.453,P <0.01). Conclusions Improved flushing pipe method can effectively extend the PICC single catheter indwelling time and reduce rate of unplanned extubation caused by drug blocking.