CAJ | 학술논문

目的：探讨肺良性转移性子宫平滑肌瘤(benign metastasizing leiomyoma，BML)的临床病理学特点及临床治疗。方法：对1例肺良性转移性子宫平滑肌瘤进行临床资料、病理形态学形态及免疫组织化学观察，并结合文献对其诊断及鉴别诊断、临床治疗、预后进行探讨。结果：肿瘤形态类似子宫平滑肌瘤，瘤细胞呈梭形，无细胞的非典型性，未见坏死，核分裂像罕见。免疫组织化学染色示肿瘤细胞：ER、PR、SMA、Calponin强阳性。结论：BML非常罕见，肺是常见转移部位，因缺乏对其认识，易与其他肿瘤混淆导致误诊。提高对BML的认识对避免误诊非常重要。
목적：탐토폐량성전이성자궁평활기류(benign metastasizing leiomyoma，BML)적림상병이학특점급림상치료。방법：대1례폐량성전이성자궁평활기류진행림상자료、병리형태학형태급면역조직화학관찰，병결합문헌대기진단급감별진단、림상치료、예후진행탐토。결과：종류형태유사자궁평활기류，류세포정사형，무세포적비전형성，미견배사，핵분렬상한견。면역조직화학염색시종류세포：ER、PR、SMA、Calponin강양성。결론：BML비상한견，폐시상견전이부위，인결핍대기인식，역여기타종류혼효도치오진。제고대BML적인식대피면오진비상중요。
Objective: To explore the characteristics of clinicopathology, diagnostic criteria and differential diagnosis of benign metastasizing leiomyoma (BML).Methods: The clinical data, histopathologic observation and immunohistochemical staining were studied in one case of BML, the related literatures were reviewed. Results:Microscopic examination of this case showed that the morphology was similar to the uterine leiomyoma, and the tumor was composed of spindle cell without marked nuclear atypia and mitosis. Immunohistochemically, ER, PR, SMA, and calponin were strong positive.Conclusion: BML is very rare tumor, and the lung is the major site of metastasis. It is easily confused with other tumor leading to misdiagnosis. It is essential to avoid misdiagnosis with raising awareness.