CAJ | 학술논문

探讨血清骨保护素（OPG）对冠脉介入术（PCI）患者预后的预测价值。选择2011年2月至2013年12月河北医科大学第三医院心内科行PCI的老年冠心病患者125例。检测不同时刻血清OPG水平（PCI术前、术后即刻、术后24小时、术后48小时、术后72小时，以及术后1个月、术后3个月、术后6个月，共8个时间点），记录术后6个月内心血管事件及支架内再狭窄情况。O PG水平和支架内再狭窄高度相关（O R＝2．02，P＜0．05）。O PG水平高者的心血管事件发生率大。血清OPG水平对PCI术后6个月的心血管事件和支架内再狭窄有较好的预测价值。
탐토혈청골보호소（OPG）대관맥개입술（PCI）환자예후적예측개치。선택2011년2월지2013년12월하북의과대학제삼의원심내과행PCI적노년관심병환자125례。검측불동시각혈청OPG수평（PCI술전、술후즉각、술후24소시、술후48소시、술후72소시，이급술후1개월、술후3개월、술후6개월，공8개시간점），기록술후6개월내심혈관사건급지가내재협착정황。O PG수평화지가내재협착고도상관（O R＝2．02，P＜0．05）。O PG수평고자적심혈관사건발생솔대。혈청OPG수평대PCI술후6개월적심혈관사건화지가내재협착유교호적예측개치。
To explore the value of osteoprotegerin (OPG ) in prediction of cardiovascular events and restenosis of elderly coronary heart disease patients after percutaneous coronary intervention (PCI) from February 2011 to December 2013 in the Third Affiliated Hospital of Hebei Medical University .Serum OPG concentration of 125 individuals who underwent PCI was evaluated at different time ,including PCI preoperative ,postoperative immediately ,24h ,48h ,72h ,1 month ,3 months and 6 months after operation ,a total of 8 points .Cardiovascular events and ISR were recorded in 6 months after stenting by coronary angiograms .The results showed baseline OPG serum concentration ,measured before PCI ,was higher in ISR patients than those without ISR .The patients with higher OPG values were more susceptible to develop ISR (odd ratio ,2 .02;P<0 .05) and at high risk for cardiovascular events .OPG serum level may be used as a clinically useful predictor for prognosis of elderly patients after PCI .