CAJ | 학술논문

比较机械通气的患者，应用右美托咪定和咪达唑仑进行镇静治疗的效果。机械通气的患者分为右美托咪定组和咪达唑仑组，回顾性分析治疗前后的临床资料。右美托咪定组和咪达唑仑组机械通气时间的比较，差异无统计学意义（P＞0．05）。两组患者谵妄的发生率、阿片类药物的使用率、药物停止至唤醒所需要的时间、循环系统不良反应的例数比较，差异有统计学意义（P＜0．05）。右美托咪定用于机械通气患者的镇静治疗，易于从镇静状态中恢复，降低谵妄的发生率，但可引起血压、心率的下降。应用咪达唑仑的患者可以减少阿片类药物的使用，循环系统不良反应的发生率较右美托咪定低。右美托咪定和咪达唑仑可作为IC U的镇静药物。
비교궤계통기적환자，응용우미탁미정화미체서륜진행진정치료적효과。궤계통기적환자분위우미탁미정조화미체서륜조，회고성분석치료전후적림상자료。우미탁미정조화미체서륜조궤계통기시간적비교，차이무통계학의의（P＞0．05）。량조환자섬망적발생솔、아편류약물적사용솔、약물정지지환성소수요적시간、순배계통불량반응적례수비교，차이유통계학의의（P＜0．05）。우미탁미정용우궤계통기환자적진정치료，역우종진정상태중회복，강저섬망적발생솔，단가인기혈압、심솔적하강。응용미체서륜적환자가이감소아편류약물적사용，순배계통불량반응적발생솔교우미탁미정저。우미탁미정화미체서륜가작위IC U적진정약물。
To evaluate the difference between exmedetomidine and midazolam of among mechanical ventilation patients . Patients were divided into exmedetomidine group and midazolam group ,and retrospective clinical data was analyzed .The incidence of delirium and arousal time were statistically significant in group exmedetomidine .And the use of opioid rate and the adverse reaction of the circulatory system were statistically significant in group midazolam . But the mechanical ventilation time were not statistically significant (P>0 .05) .In exmedetomidine group ,patients were prone to recovery from sedation ,and delirium did not easily occur .In midazolam group ,patients needed a few opioids ,and the adverse reaction of the circulatory system happened less .Exmedetomidine and midazolam are effective sedative drugs .