中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
EVALUATION AND ANAL YSIS OF DRUG-USE IN HOSPITALS OF CHINA
2015年
6期
791-793
,共3页
乳房/外科学%手术期间%抗菌药物%预防性使用
乳房/外科學%手術期間%抗菌藥物%預防性使用
유방/외과학%수술기간%항균약물%예방성사용
Breast surgery%Perioperative period%Antibiotics%Analysis of drug use
目的：了解某院乳腺手术患者预防性抗菌药物应用现状及合理性，为加强围术期抗菌药物合理使用和规范管理提供依据。方法：采用回顾性调查方法，查阅某院2013年出院的全部乳腺Ⅰ类切口手术患者病历573份，剔除手术前、后存在细菌感染或与手术无关的细菌感染的无效样本，对有效样本的患者年龄、性别、住院时间、临床诊断、手术时间、抗菌药物使用品种、用药时间、用法及用量、给药途径、给药阶段等进行统计分析。结果：557例患者乳腺手术时间以1．0～2．0 h为主，共230例，占41．29％；＞3．0 h者82例，占14．72％。围术期预防性应用抗菌药物119例，使用率为21．36％；术前0．5～2．0 h用药34例，占28．57％；术后使用82例，占68．91％；术后用药时间＞48 h者2例。预防性使用抗菌药物品种以五水头孢唑啉钠为主，占99．16％。结论：某院乳腺手术患者预防性应用抗菌药物在药物适应证控制、用药时间及用药疗程的把握、药物品种的选择等方面均基本合理。
目的：瞭解某院乳腺手術患者預防性抗菌藥物應用現狀及閤理性，為加彊圍術期抗菌藥物閤理使用和規範管理提供依據。方法：採用迴顧性調查方法，查閱某院2013年齣院的全部乳腺Ⅰ類切口手術患者病歷573份，剔除手術前、後存在細菌感染或與手術無關的細菌感染的無效樣本，對有效樣本的患者年齡、性彆、住院時間、臨床診斷、手術時間、抗菌藥物使用品種、用藥時間、用法及用量、給藥途徑、給藥階段等進行統計分析。結果：557例患者乳腺手術時間以1．0～2．0 h為主，共230例，佔41．29％；＞3．0 h者82例，佔14．72％。圍術期預防性應用抗菌藥物119例，使用率為21．36％；術前0．5～2．0 h用藥34例，佔28．57％；術後使用82例，佔68．91％；術後用藥時間＞48 h者2例。預防性使用抗菌藥物品種以五水頭孢唑啉鈉為主，佔99．16％。結論：某院乳腺手術患者預防性應用抗菌藥物在藥物適應證控製、用藥時間及用藥療程的把握、藥物品種的選擇等方麵均基本閤理。
목적：료해모원유선수술환자예방성항균약물응용현상급합이성，위가강위술기항균약물합리사용화규범관리제공의거。방법：채용회고성조사방법，사열모원2013년출원적전부유선Ⅰ류절구수술환자병력573빈，척제수술전、후존재세균감염혹여수술무관적세균감염적무효양본，대유효양본적환자년령、성별、주원시간、림상진단、수술시간、항균약물사용품충、용약시간、용법급용량、급약도경、급약계단등진행통계분석。결과：557례환자유선수술시간이1．0～2．0 h위주，공230례，점41．29％；＞3．0 h자82례，점14．72％。위술기예방성응용항균약물119례，사용솔위21．36％；술전0．5～2．0 h용약34례，점28．57％；술후사용82례，점68．91％；술후용약시간＞48 h자2례。예방성사용항균약물품충이오수두포서람납위주，점99．16％。결론：모원유선수술환자예방성응용항균약물재약물괄응증공제、용약시간급용약료정적파악、약물품충적선택등방면균기본합리。
OBJECTIVE:To investigate the status quo of the prophylactic use of antibiotics in patients undergoing breast surgery so as to provide guidance for rational use and standardized management of antibiotics.METHODS:Using the method of retrospective investigation, a total of 573 medical records of patients undergoing type I incision surgery (breast surgery) during 2013 were collected.The exclusion criteria were cases presenting with bacterial infection before and after operation or independent of operation.The valid samples were analzyed statistically with regard to patients'age, sex, hosptial stay, clincal diagnosis, operation time, types of antibiotics used, medication time, usage and dosage, administration route, stage of medicaiton etc.RESULTS:Of the 557 valid cases, the duration of breast surgery in 230 cases (41.29%) stood at 1-2 hours, with >3.0 h noted in 82 (14.72%).119 cases (21.36%) had perioperative prophylactic use of antibiotics, with 34 (28.75%) received antibiotics at 30 min-2 hours before the surgey and 82 (68.91%) cases received antibioics after surgey. 2 cases had postoperative use of antibiotics for duration of more than 48 hours.Cefazolin Sodium Pentahydrate Cefazolin was the predominantly used prophylactic antibiotics, accouting for 99.16%.CONCLUSIONS:The prophylactic use of antibiotics in patients undergoing breast surgery was rational on the whole in terms of indications, time and duration of administration and the choice of drug types etc.
