CAJ | 학술논문

目的：探讨腹腔镜联合新辅助化疗（CRT）在中低位直肠癌治疗中的效果。方法选取20例行腹腔镜手术＋CRT 的中低位直肠癌病例（治疗组），另随机抽取同期收治的行腹腔镜手术的直肠癌病例30例（对照组）。对2组临床资料和手术学资料进行比较分析。结果新辅助化疗组淋巴清扫数目[（10．6±5．2）枚]低于对照组[（15．4±6．9）枚]；治疗组保肛率为92．5％（74／80），高于对照组80．8％（97／120），差异均有统计学意义（P ＜0．05）。2组在手术时间、术中出血、肛门排气时间、远端切缘阳性、中转开腹、术后并发症发生等方面无统计学差异。治疗组与对照组生存率和无瘤生存率差异无统计学意义。结论腹腔镜联合 CRT 治疗中低位直肠癌是安全、可行的，具有与单纯腹腔镜手术相同的手术学结果。
목적：탐토복강경연합신보조화료（CRT）재중저위직장암치료중적효과。방법선취20례행복강경수술＋CRT 적중저위직장암병례（치료조），령수궤추취동기수치적행복강경수술적직장암병례30례（대조조）。대2조림상자료화수술학자료진행비교분석。결과신보조화료조림파청소수목[（10．6±5．2）매]저우대조조[（15．4±6．9）매]；치료조보항솔위92．5％（74／80），고우대조조80．8％（97／120），차이균유통계학의의（P ＜0．05）。2조재수술시간、술중출혈、항문배기시간、원단절연양성、중전개복、술후병발증발생등방면무통계학차이。치료조여대조조생존솔화무류생존솔차이무통계학의의。결론복강경연합 CRT 치료중저위직장암시안전、가행적，구유여단순복강경수술상동적수술학결과。
Objective To evaluate the efficacy of laparoscopic surgery following neoadjuvant chemoradiotherapy (CRT) for mid-low rectal cancer.Methods 20 patients with mid-low rectal cancer received laparoscopic total mesorectal excision (TME) after neoadjuvant CRT was the treatment group .Another 30 patients with mid-low rectal cancer received primary laparo -scopic TME was the control group .The clinical data and surgical data of the 2 groups of patients were collected and analyzed com -paratively.Results Lymph node yield in the treatment group was significantly lower than that of the control group (10.6 ±5.2 vs 15.4 ±6.9,P <0.05).Guarantor anus rate in the treatment group was significantly higher than that of the control group [92.5%(74 /80) vs 80.8% (97 /120)].There was no difference between the 2 groups in the operative time,intraoperative blood loss,intestinal function recovery,positive surgical margins,rate of conversion to open surgery ,and occurrence of postopera -tive complications.There was no difference in the survival rate and disease -free survival rate between the 2 groups.Conclusion Laparoscopic surgery and neoadjuvant CRT for mid -low rectal cancer is safe and feasible ,it produce similar surgical outcome as exclusive laparoscopic surgery.