CAJ | 학술논문

目的探讨阿尔茨海默病（ AD）与血管性痴呆（ VD）患者精神行为症状（ BPSD）的阳性检出率及差异。方法选取2011年1月-2014年6月在临沂市精神卫生中心住院的痴呆患者，均符合美国精神病学会《精神障碍诊断和统计手册（第4版）》（ DSM-Ⅳ）AD和VD诊断标准，其中AD患者102例，VD患者100例，采用简易精神状态评定量表（ MMSE）及神经精神问卷（ NPI）进行测评。结果 AD和VD患者BPSD阳性检出率分别为92.16%和86.00%，差异无统计学意义（χ2=1.972，P﹥0.05）。AD组幻觉、激越、淡漠、易激惹、异常运动行为、睡眠夜间行为的阳性检出率高于VD组，差异有统计学意义（ P﹤0.05或0.01），VD组抑郁症状检出率高于AD组，差异有统计学意义（ P﹤0.01）。结论 AD和VD患者BPSD存在差异，对BPSD测评可能有助于AD和VD的鉴别。
목적탐토아이자해묵병（ AD）여혈관성치태（ VD）환자정신행위증상（ BPSD）적양성검출솔급차이。방법선취2011년1월-2014년6월재림기시정신위생중심주원적치태환자，균부합미국정신병학회《정신장애진단화통계수책（제4판）》（ DSM-Ⅳ）AD화VD진단표준，기중AD환자102례，VD환자100례，채용간역정신상태평정량표（ MMSE）급신경정신문권（ NPI）진행측평。결과 AD화VD환자BPSD양성검출솔분별위92.16%화86.00%，차이무통계학의의（χ2=1.972，P﹥0.05）。AD조환각、격월、담막、역격야、이상운동행위、수면야간행위적양성검출솔고우VD조，차이유통계학의의（ P﹤0.05혹0.01），VD조억욱증상검출솔고우AD조，차이유통계학의의（ P﹤0.01）。결론 AD화VD환자BPSD존재차이，대BPSD측평가능유조우AD화VD적감별。
Objective To explore the prevalence and difference of kehavioral and psychological symptoms( BPSD)in patients with Alzheimer ˊs disease( AD)and patients with vascular dementia( VD). Methods 102 inpatients with AD and 100 inpatients with VD in accord with Diagnostic and Statistical Manual of Mental disorders,Fourth Edition( DSM-Ⅳ)in Linyi Mental Health Center were enrolled from January,2011 to June,2014. All patients were assessed with Mini Mental State Examination(MMSE)and Neuropsy=chiatric Inventory(NPI). Results The prevalence of BPSD in patients with AD and patients with VD were 92. 16%,86. 00% respec=tively,there was no difference ketween the two groups(χ2 =1. 972,P﹥0. 05). The rate of hallucinations,agitation,apathy,irritakility, akerrant motor kehavior,sleep kehavior in AD group was significantly higher than that in VD group(P﹤0. 05 or 0. 01),while the rate of depression symptoms were more common in VD group than in AD group(P﹤0. 01). Conclusion There is difference of BPSD in patients with AD and patients with VD,and itˊs helpful to distinguish AD and VD patients ky evaluating BPSD.