CAJ | 학술논문

目的：提高对肺粪类圆线虫感染的认识。方法：分析湖南省湘雅医院呼吸ICU确诊的2例肺粪类圆线虫重度感染患者的临床表现、实验室检测、影像学及病理学资料，并复习1973年至2013年国内报道的87个案例。结果：本次发现的2例患者均为消化道症状起病，仅在肺发现粪类圆线虫。89例死亡病例血常规检测中有嗜酸性粒细胞(EOS)的13例，其中10例EOS≤0.05×109/L。结论：农民为主要感染者。患有基础疾病或长期接受糖皮质激素治疗使机体免疫低下的患者感染粪类圆线虫后容易发展成重症感染致死。患者EOS减少提示预后较差，需早期诊断和治疗。
목적：제고대폐분류원선충감염적인식。방법：분석호남성상아의원호흡ICU학진적2례폐분류원선충중도감염환자적림상표현、실험실검측、영상학급병이학자료，병복습1973년지2013년국내보도적87개안례。결과：본차발현적2례환자균위소화도증상기병，부재폐발현분류원선충。89례사망병례혈상규검측중유기산성립세포(EOS)적13례，기중10례EOS≤0.05×109/L。결론：농민위주요감염자。환유기출질병혹장기접수당피질격소치료사궤체면역저하적환자감염분류원선충후용역발전성중증감염치사。환자EOS감소제시예후교차，수조기진단화치료。
Objective: To improve the understanding of pulmonaryStrongyloides stercoralis. Methods: Two paients were diagnosed with severe infection with pulmonaryStrongyloides stercoralis by respiratory ICU of Xiangya Hospital. The clinical manifestations, laboratory tests, imaging and pathological data were analyzed. Another 87 cases in the literature were reviewed from 1973 to 2013. Results: In the 2 cases, digestive symptoms were the ifrst symptom andStrongyloides stercoralis was found in the lungs. Eosinophils was detected in the 13 death cases by blood routine examination, with 10 cases≤0.05×109/L. Conclusion: The farmers were the main infected people. Patients with basic diseases or with immunosuppression due to long-term glucocorticoid treatment tend to infect and even die atfer the infection withStrongyloides stercoralis. Eosinophil granulocyte reduction shows poor prognosis, which needs early diagnosis and treatment.