CAJ | 학술논문

目的探讨布-加综合征(B-CS)患者并发脾动脉瘤的相关危险因素.方法回顾性分析郑州大学第一附属医院2010年7月至2014年10月收治的11例B-CS并发脾动脉瘤患者的临床资料.随机选取同期收治的60例B-CS未并发脾动脉瘤患者作为对照组.分析两组患者的年龄、性别、吸烟史、饮酒史、高血压史、B-CS类型、门静脉主干内径、脾动脉主干内径、脾静脉主干内径、脾脏厚度及脾脏长径,采用单因素分析及非条件Logistic回归模型筛选B-CS并发脾动脉瘤的危险因素.结果单因素分析显示脾动脉瘤组与非脾动脉瘤组患者在年龄、性别、吸烟史、饮酒史、高血压史、B-CS类型、门静脉主干内径、脾静脉主干内径上差别均无统计学意义(P＞0.05),脾动脉瘤组患者的脾动脉主干内径、脾脏厚度及脾脏长径明显大于非脾动脉瘤组患者,差异有统计学意义(P＜0.05).非条件Logistic回归模型分析结果显示性别、脾脏厚度是B-CS并发脾动脉瘤的独立危险因素(OR值分别为0.081、1.151,均P＜0.05).结论 B-CS并发脾动脉瘤的发生可能与脾动脉主干内径、脾脏长径及厚度的增加有关,性别及脾脏厚度是其独立危险因素.
목적 탐토포-가종합정(B-CS)환자병발비동맥류적상관위험인소.방법 회고성분석정주대학제일부속의원2010년7월지2014년10월수치적11례B-CS병발비동맥류환자적림상자료.수궤선취동기수치적60례B-CS미병발비동맥류환자작위대조조.분석량조환자적년령、성별、흡연사、음주사、고혈압사、B-CS류형、문정맥주간내경、비동맥주간내경、비정맥주간내경、비장후도급비장장경,채용단인소분석급비조건Logistic회귀모형사선B-CS병발비동맥류적위험인소.결과 단인소분석현시비동맥류조여비비동맥류조환자재년령、성별、흡연사、음주사、고혈압사、B-CS류형、문정맥주간내경、비정맥주간내경상차별균무통계학의의(P＞0.05),비동맥류조환자적비동맥주간내경、비장후도급비장장경명현대우비비동맥류조환자,차이유통계학의의(P＜0.05).비조건Logistic회귀모형분석결과현시성별、비장후도시B-CS병발비동맥류적독립위험인소(OR치분별위0.081、1.151,균P＜0.05).결론 B-CS병발비동맥류적발생가능여비동맥주간내경、비장장경급후도적증가유관,성별급비장후도시기독립위험인소.
Objective To investigate the risk factors of Budd-Chiari syndrome (B-CS) complicated with splenic artery aneurysms.Methods The clinical data of 11 patients with B-CS complicated with splenic artery aneurysms treated in the First Affiliated Hospital of Zhengzhou University from July 2010 to October 2014 were retrospectively analyzed.60 other patients treated in the same study period were selected randomly to form a control group.The age,gender,smoking history,drinking history,hypertension history,type of B-CS,portal vein diameter,splenic artery diameter,splenic vein diameter,splenic length and splenic thickness were recorded and analyzed.Univariate analysis and unconditional logistic regression model were performed to find out the risk factors.Results Univariate analysis showed that there were no statistical differences in age,gender,smoking history,drinking history,hypertension history,type of B-CS,portal vein diameter and splenic vein diameter between the two groups (P ＞ 0.05).However,the splenic artery diameter,splenic length and splenic thickness in the splenic artery aneurysms group were obviously higher than that in the non-splenic artery aneurysms group.The differences were significant (P ＜ 0.05).The results of unconditional logistic regression model analysis indicated that gender and splenic thickness were independent risk factors of B-CS complicated with splenic artery aneurysms (OR =0.081,1.151;all P ＜ 0.05).Conclusions B-CS complicated with splenic artery aneurysms was correlated with an increase in splenic artery diameter,splenic length and splenic thickness.Gender and splenic thickness were independent risk factors.