CAJ | 학술논문

目的：对比分析精神分裂症患者与其一级亲属在社会认知功能方面存在的差异。方法随机选取100名精神分裂患者和该100名患者一级亲属,调查他们的一般资料,并进行威斯康星卡片分类测验、持续操作测验和韦氏成人记忆量表修订版的测评。通过 t 检验和卡方检验比较患者组和亲属组认知功能的差异。结果无论是亲属组还是患者组,均有超过一半的人存在工作记忆-执行功能缺陷,但两组存在工作记忆-执行功能缺陷的概率差异有统计学意义,患者组存在工作记忆-执行功能缺陷的比例高于亲属组(χ2=4.582,P =0.032)；而两组人群的注意障碍(χ2=1.496,P =0.221)和记忆障碍的差异无统计学意义(χ2=3.380,P =0.066)。结论与精神分裂症患者相比,其一级亲属存在工作-执行功能缺陷的比例较低,但存在同样风险的注意障碍和记忆障碍。
목적：대비분석정신분렬증환자여기일급친속재사회인지공능방면존재적차이。방법수궤선취100명정신분렬환자화해100명환자일급친속,조사타문적일반자료,병진행위사강성잡편분류측험、지속조작측험화위씨성인기억량표수정판적측평。통과 t 검험화잡방검험비교환자조화친속조인지공능적차이。결과무론시친속조환시환자조,균유초과일반적인존재공작기억-집행공능결함,단량조존재공작기억-집행공능결함적개솔차이유통계학의의,환자조존재공작기억-집행공능결함적비례고우친속조(χ2=4.582,P =0.032)；이량조인군적주의장애(χ2=1.496,P =0.221)화기억장애적차이무통계학의의(χ2=3.380,P =0.066)。결론여정신분렬증환자상비,기일급친속존재공작-집행공능결함적비례교저,단존재동양풍험적주의장애화기억장애。
Objectives To investigate whether there are differences in cognitive function between schizophrenia patients and their first-degree relatives.Methods 100 schizophrenia patients and 100 corresponding first-degree relatives were selected.We investigated the demographic characteristics of the respondents,and conducted Wisconsin card sorting test,Wech-sler memory scale,and continuous performance test.T test and Chi-square test were applied to identify the potential difference in cognitive function between schizophrenia patients and their first-degree relatives.Results More than half of the respondents in the two groups experienced working memory-executive function defect,and the difference was statistically significant (χ2 =4.582,P =0.032).There are no obvious differences in attention dysfunction and memory impairment between the two groups (χ2 =1.496,P =0.221 andχ2 =3.380,P =0.066).Conclusions Compared with schizophrenia patients,their first-degree rel-atives were less likely to experience working memory-executive function defect,but schizophrenia patients and their first-degree relatives had the same risk of attention dysfunction and memory impairment.