安徽医学
安徽醫學
안휘의학
ANHUI MEDICAL JOURNAL
2015年
6期
717-720
,共4页
同型半胱氨酸%脑微出血%高血压%危险因素%卒中
同型半胱氨痠%腦微齣血%高血壓%危險因素%卒中
동형반광안산%뇌미출혈%고혈압%위험인소%졸중
Homocysteine%Cerebral microbleeds%Hypertension%Risk factors%Stroke
目的：探讨急性脑梗死患者血浆同型半胱氨酸( Hcy)水平、高血压与脑微出血( CMB)的关系。方法选择铜陵市人民医院神经内科2011年1月至2012年1月收治的急性脑梗死患者74例,对其临床及影像学资料进行回顾性分析。根据是否存在CMB分为CMB组和无CMB组。记录两组患者血压、血脂、血糖、血浆Hcy水平等情况,并探讨CMB的危险因素。结果74例急性脑梗死患者中,男性51例,女性23例,平均(66．22±8．96)岁。 logistic回归分析显示,CMB的发生与高血压密切相关(OR=4．67,95% CI ∶1．23~17．65,P=0．02),与血浆Hcy水平无明显相关(OR=1．01,95% CI ∶0．97~1．06,P=0．38)。结论 CMB与血浆Hcy水平增高无关,与高血压显著相关,高血压可能为其独立危险因素。
目的：探討急性腦梗死患者血漿同型半胱氨痠( Hcy)水平、高血壓與腦微齣血( CMB)的關繫。方法選擇銅陵市人民醫院神經內科2011年1月至2012年1月收治的急性腦梗死患者74例,對其臨床及影像學資料進行迴顧性分析。根據是否存在CMB分為CMB組和無CMB組。記錄兩組患者血壓、血脂、血糖、血漿Hcy水平等情況,併探討CMB的危險因素。結果74例急性腦梗死患者中,男性51例,女性23例,平均(66．22±8．96)歲。 logistic迴歸分析顯示,CMB的髮生與高血壓密切相關(OR=4．67,95% CI ∶1．23~17．65,P=0．02),與血漿Hcy水平無明顯相關(OR=1．01,95% CI ∶0．97~1．06,P=0．38)。結論 CMB與血漿Hcy水平增高無關,與高血壓顯著相關,高血壓可能為其獨立危險因素。
목적：탐토급성뇌경사환자혈장동형반광안산( Hcy)수평、고혈압여뇌미출혈( CMB)적관계。방법선택동릉시인민의원신경내과2011년1월지2012년1월수치적급성뇌경사환자74례,대기림상급영상학자료진행회고성분석。근거시부존재CMB분위CMB조화무CMB조。기록량조환자혈압、혈지、혈당、혈장Hcy수평등정황,병탐토CMB적위험인소。결과74례급성뇌경사환자중,남성51례,녀성23례,평균(66．22±8．96)세。 logistic회귀분석현시,CMB적발생여고혈압밀절상관(OR=4．67,95% CI ∶1．23~17．65,P=0．02),여혈장Hcy수평무명현상관(OR=1．01,95% CI ∶0．97~1．06,P=0．38)。결론 CMB여혈장Hcy수평증고무관,여고혈압현저상관,고혈압가능위기독립위험인소。
Objective To investigate the correlation between plasma homocysteine(Hcy) level, hypertension and cerebral microb-leeds(CMBs) in patients with acute cerebral infarction. Methods The clinical and imaging data of 74 patients with acute cerebral infarction who had been admitted in this hospital from January 2011 to January 2012 were analyzed retrospectively. According to the existence of cere-bral microbleeds, the patients were divided into two groups, namely the CMB group and the non-CMB group. Blood pressure, blood lipids, blood glucose, and plasma homocysteine were recorded in the two groups of patients, and the risk factors for cerebral microbleeds in acute cerebral infarction were explored. Results A total of 74 patients with acute cerebral infarction were enrolled, 23 of them were females and 51 were males (mean age 66. 22 ± 8. 96 years). Multivariate logistic regression analysis showed that cerebral microbleeds was associated closely with hypertension(OR=4. 67,95% CI:1. 2~17. 65,P=0. 02), but plasma Hcy level was not related to CMBs(OR=1. 01,95%CI:0. 97~1. 06,P=0. 38). Conclusion The level of elevated plasma Hcy in patients with acute cerebral infarction is unrelated to CMBs. Hypertension is significantly associated with CMBs, which might be the independent risk factor for CMBs.
