CAJ | 학술논문

目的：探讨应用Solitaire AB支架机械取栓联合动脉溶栓治疗急性缺血性脑卒中的安全性及效果。方法选取2010年1月至2014年10月应用Solitaire AB支架机械取栓联合动脉溶栓治疗的18例急性缺血性脑卒中患者,评价其疗效和预后。结果18例患者经支架机械取栓结合动脉溶栓后均成功获得全部或部分再通。术前与术后美国国立卫生研究院卒中量表评分相比,差异有统计学意义(P<0．05)。3个月后疗效评估,17例改良Rankin评分(mRS)显示预后良好,其中0分10例,1分6例,2分1例；1例预后不良,mRS 4分。18例患者复查均无血管再闭塞等并发症。结论应用Solitaire AB支架机械取栓联合动脉溶栓治疗急性缺血性脑卒中是相对安全、有效的,但应严格把握手术适应证。
목적：탐토응용Solitaire AB지가궤계취전연합동맥용전치료급성결혈성뇌졸중적안전성급효과。방법선취2010년1월지2014년10월응용Solitaire AB지가궤계취전연합동맥용전치료적18례급성결혈성뇌졸중환자,평개기료효화예후。결과18례환자경지가궤계취전결합동맥용전후균성공획득전부혹부분재통。술전여술후미국국립위생연구원졸중량표평분상비,차이유통계학의의(P<0．05)。3개월후료효평고,17례개량Rankin평분(mRS)현시예후량호,기중0분10례,1분6례,2분1례；1례예후불량,mRS 4분。18례환자복사균무혈관재폐새등병발증。결론응용Solitaire AB지가궤계취전연합동맥용전치료급성결혈성뇌졸중시상대안전、유효적,단응엄격파악수술괄응증。
Objective To investigate the effectiveness and safety of mechanical thrombectomy with solitaire AB stents in combination with intra-arterial thrombolysis for treatment of acute ischemic stroke. Methods The clinical data of 18 consecutive patients with acute is-chemic stroke treated with mechanical thrombectomy, using Solitaire AB stents in combination with intra-arterial thrombolysis in our hospital from January 2010 to October 2014, were analyzed retrospectively. The patients were followed up for three months after the procedure. Re-sults Complete or part recanalization was achieved by mechanical thrombectomy with solitaire AB stents in combination with intraarterial thrombolysis in all eighteen patients. The National Institute of Health Stroke Scale ( NIHSS) score was obviously lower after treatment than before treatment, with a significant difference ( P<0. 05 ) . During the follow-up period lasting three months, 17 patients had a good mRS score, including 10 cases with a mRS score of zero, 6 cases with one and 1 case with two. One patient had a mRS score of four. Re-obstruc-tion occurred in none of the patients. Conclusion It appears to be safe and effective for endovascular treatment of acute ischemic stroke by using mechanical thrombectomy with solitaire AB stents in combination with intra-arterial thrombolysis.