中南大学学报（医学版）
中南大學學報（醫學版）
중남대학학보（의학판）
JOURNAL OF CENTRAL SOUTH UNIVERSITY (MEDICAL SCIENCES)
2014年
12期
1271-1278
,共8页
朱爱群%张静平%邹婷%熊光仲
硃愛群%張靜平%鄒婷%熊光仲
주애군%장정평%추정%웅광중
脑卒中%年龄%性别%危险因素
腦卒中%年齡%性彆%危險因素
뇌졸중%년령%성별%위험인소
stroke%age%gender%risk factors
目的：探讨血压、血糖、血脂与不同年龄、不同性别脑梗死和脑出血患者的关系。方法：采用病例对照研究收集2010年1月至2013年12月在中南大学湘雅二医院住院的初发脑梗死患者358例，脑出血患者230例为病例组，社区获得性肺炎患者165例为对照组。根据年龄将脑卒中患者分为青年组、中年组和老年组，比较3组间相关因素的差异。将脑卒中患者按性别分组，分析不同性别组之间血压、血脂、肾功能的不同。结果：非条件logistic回归结果显示：血压升高、高血压病史、糖尿病史、空腹血糖与脑梗死有关(P<0.05)；血压升高、高血压病史、LDL-C、空腹血糖、血肌酐、饮酒史与脑出血有关(P<0.05)。高血压是脑卒中的主要危险因素(青年组、中年组和老年组OR值分别为10.43，4.74和7.39，P<0.01)。收缩压升高是青年组重要的危险因素(OR=28.74)。舒张压、糖尿病史仅与中年组脑卒中有关(OR值分别为2.96，6.25)。LDL-C与老年组脑卒中相关(OR=2.87)。不同性别脑卒中单因素分析结果显示：脑梗死患者的舒张压男性高于女性，脑出血患者TC，HDL-C，LDL-C女性高于男性(P<0.05)。结论：青年脑卒中的高危因素主要为高血压、尤其收缩压升高，中年患者与高血压、糖尿病有关，而老年患者则是高血压、糖尿病、饮酒以及LDL-C等多种因素共同作用的结果。
目的：探討血壓、血糖、血脂與不同年齡、不同性彆腦梗死和腦齣血患者的關繫。方法：採用病例對照研究收集2010年1月至2013年12月在中南大學湘雅二醫院住院的初髮腦梗死患者358例，腦齣血患者230例為病例組，社區穫得性肺炎患者165例為對照組。根據年齡將腦卒中患者分為青年組、中年組和老年組，比較3組間相關因素的差異。將腦卒中患者按性彆分組，分析不同性彆組之間血壓、血脂、腎功能的不同。結果：非條件logistic迴歸結果顯示：血壓升高、高血壓病史、糖尿病史、空腹血糖與腦梗死有關(P<0.05)；血壓升高、高血壓病史、LDL-C、空腹血糖、血肌酐、飲酒史與腦齣血有關(P<0.05)。高血壓是腦卒中的主要危險因素(青年組、中年組和老年組OR值分彆為10.43，4.74和7.39，P<0.01)。收縮壓升高是青年組重要的危險因素(OR=28.74)。舒張壓、糖尿病史僅與中年組腦卒中有關(OR值分彆為2.96，6.25)。LDL-C與老年組腦卒中相關(OR=2.87)。不同性彆腦卒中單因素分析結果顯示：腦梗死患者的舒張壓男性高于女性，腦齣血患者TC，HDL-C，LDL-C女性高于男性(P<0.05)。結論：青年腦卒中的高危因素主要為高血壓、尤其收縮壓升高，中年患者與高血壓、糖尿病有關，而老年患者則是高血壓、糖尿病、飲酒以及LDL-C等多種因素共同作用的結果。
목적：탐토혈압、혈당、혈지여불동년령、불동성별뇌경사화뇌출혈환자적관계。방법：채용병례대조연구수집2010년1월지2013년12월재중남대학상아이의원주원적초발뇌경사환자358례，뇌출혈환자230례위병례조，사구획득성폐염환자165례위대조조。근거년령장뇌졸중환자분위청년조、중년조화노년조，비교3조간상관인소적차이。장뇌졸중환자안성별분조，분석불동성별조지간혈압、혈지、신공능적불동。결과：비조건logistic회귀결과현시：혈압승고、고혈압병사、당뇨병사、공복혈당여뇌경사유관(P<0.05)；혈압승고、고혈압병사、LDL-C、공복혈당、혈기항、음주사여뇌출혈유관(P<0.05)。고혈압시뇌졸중적주요위험인소(청년조、중년조화노년조OR치분별위10.43，4.74화7.39，P<0.01)。수축압승고시청년조중요적위험인소(OR=28.74)。서장압、당뇨병사부여중년조뇌졸중유관(OR치분별위2.96，6.25)。LDL-C여노년조뇌졸중상관(OR=2.87)。불동성별뇌졸중단인소분석결과현시：뇌경사환자적서장압남성고우녀성，뇌출혈환자TC，HDL-C，LDL-C녀성고우남성(P<0.05)。결론：청년뇌졸중적고위인소주요위고혈압、우기수축압승고，중년환자여고혈압、당뇨병유관，이노년환자칙시고혈압、당뇨병、음주이급LDL-C등다충인소공동작용적결과。
Objective: To investigate the relationship between blood pressure, blood glucose or blood lipids and patients with cerebral infarction (CI) or intracerebral hemorrhage (ICH) in diff erent age or gender. Methods: hT e case-control study consecutively recruited patients with if rst-ever-in-a-lifetime CI (n=358) and ICH (n=230) and community-acquired pneumonia (n=165) as controls between January 2010 and December 2013 at the Second Xiangya Hospital of Central South University. hT epatients with CI or ICH were divided into the young group, the middle-aged group and the older group, and the risk factors were compared between the 3 groups. hTe patients with CI or ICH were respectively further divided into the male group and the female group. hTe blood pressure, glucose and lipids were measured. Results: Data from logistic regression models showed that CI was closely associated with high blood pressure, hypertension, diabetes mellitus (DM) or fasting plasma glucose (FPG) (P<0.05), and ICH was closely related to high blood pressure, hypertension, low density lipoprotein-cholesterol (LDL-C), FPG, serum creatinine (SCr) or alcohol drinking (P<0.05); hypertension was the main risk factor for stroke. hTe odds ratios for the young, the middle-aged and older group were 10.43, 4.74 and 7.39 respectively (P<0.05). Systolic blood pressure (OR=28.74) was the important risk factor for the young stroke, and the OR is 2.81 for the middle-aged stroke. Diastolic blood pressure (OR=2.96) and DM (OR=6.25) were the risk factor for the middle-aged stroke. LDL-C (OR=2.87) was a risk factor for the older stroke; the mean levels of diastolic blood pressure in males were signiifcantly increased compared with that in females with CI, while the mean levels of TC, HDL-C or LDL-C in females were signiifcantly higher than that in males with ICH (P<0.05). Conclusion: Hypertension, systolic blood pressure in particular, is the most common risk factor for young stroke patients. DM and hypertension are the risk factors for the middle-aged patients, while hypertension, DM, LDL-C and alcohol consuming are the risk factors for the aged patients.
