CAJ | 학술논문

目的：探讨超声造影法在乳腺癌术中检测前哨淋巴结（SLN）的可行性及临床应用价值。方法选择21例乳腺癌根治术患者，术中于肿瘤周围注射1％亚甲蓝，寻找被蓝染的 SLN；于相同注射部位注射超声造影剂声诺维（SonoVue），动态观察并标记显像 SLN。对比超声造影法和亚甲蓝法对 SLN 的检出率和准确率。结果注射 SonoVue 后能够获得清晰的传人淋巴管和 SLN 图像。超声造影法对乳腺癌患者 SLN 的检出率为85．71％，准确率为89．29％；亚甲蓝法对其检出率为80．95％，准确率为93．33％，2种方法检出率和准确率比较差异均无统计学意义（P ＞0．05）。结论超声造影法在乳腺癌患者 SLN 检查中具有与亚甲蓝法同样的临床价值。
목적：탐토초성조영법재유선암술중검측전초림파결（SLN）적가행성급림상응용개치。방법선택21례유선암근치술환자，술중우종류주위주사1％아갑람，심조피람염적 SLN；우상동주사부위주사초성조영제성낙유（SonoVue），동태관찰병표기현상 SLN。대비초성조영법화아갑람법대 SLN 적검출솔화준학솔。결과주사 SonoVue 후능구획득청석적전인림파관화 SLN 도상。초성조영법대유선암환자 SLN 적검출솔위85．71％，준학솔위89．29％；아갑람법대기검출솔위80．95％，준학솔위93．33％，2충방법검출솔화준학솔비교차이균무통계학의의（P ＞0．05）。결론초성조영법재유선암환자 SLN 검사중구유여아갑람법동양적림상개치。
Objective To study the feasibility of contrast enhanced ultrasonography (CEUS)in detecting sentinel lymph node (SLN)in patients with breast cancer during operation and its clinical significance. Methods 21 patients who underwent radical resection of a primary breast cancer were enrolled.During op-eration,1% methylene blue was injected around the tumor,and SLN mapping was performed.Then the SonoVue was injected at the same sites,then CEUS was performed to observe changes of SLN in real time, and marked them.The SLN detection rate and accuracy of CEUS were compared to those of conventional dye guided method.Results SLN were successfully imaged by SonoVue,the detection rate of CEUS for SLN was 80.95%,and the accuracy was 93.55%.The detection rate of dye guided method for SLN was 85.71%,and the accuracy was 93.75%,there was no statistically significant difference between CEUS and dye guided method (P >0.05).Conclusion Peritumoral injection is a good method for evaluating and pre-dicting sentinel lymph nodes in breast cancer.When injected SonoVue in peritumoral,the good mapping of SLN in patients with breast cancer can be obtained,and it will play an important role in clinical application to map SLN in patients with breast cancer.