CAJ | 학술논문

目的：探讨莫沙必利联合埃索美拉唑治疗反流性食管炎的临床疗效。方法选取我院在2013年8月到2015年2月收治的77例反流性食管炎患者，按照随机法将其分为两组，观察组40例，应用莫沙必利联合埃索美拉唑治疗，对照组37例，应用兰索拉唑治疗，对比两组患者的治疗效果。结果观察组40例患者中，治疗有效率为92.5％，出现不良反应的有3例，发生率为7.5％，对照组37例患者中，治疗有效率为78.38％，出现不良反应的有7例，发生率为18.92％，观察组的治疗有效率显著高于对照组，不良反应发生率显著低于对照组，差异有统计学意义（P <0.05）。结论临床应用莫沙必利联合埃索美拉唑治疗反流性食管炎的效果显著，而且不良反应发生较少，值得推广应用。
목적：탐토막사필리연합애색미랍서치료반류성식관염적림상료효。방법선취아원재2013년8월도2015년2월수치적77례반류성식관염환자，안조수궤법장기분위량조，관찰조40례，응용막사필리연합애색미랍서치료，대조조37례，응용란색랍서치료，대비량조환자적치료효과。결과관찰조40례환자중，치료유효솔위92.5％，출현불량반응적유3례，발생솔위7.5％，대조조37례환자중，치료유효솔위78.38％，출현불량반응적유7례，발생솔위18.92％，관찰조적치료유효솔현저고우대조조，불량반응발생솔현저저우대조조，차이유통계학의의（P <0.05）。결론림상응용막사필리연합애색미랍서치료반류성식관염적효과현저，이차불량반응발생교소，치득추엄응용。
Objective Clinical efect of mosapride combined with esomeprazole medication in treatment of reflux esophagitis is to be analyzed and studied.MethodsChoose 77 patients of reflux esophagitis who are treated in hospital from August 2013 to February 2015 and separate them into two groups at random, 40 patients in study group are given mosapride combined with esomeprazole medication treatment, while 37 patients in control group are given lansoprazole medication treatment, and then compare treatment efects between two groups.Results40 patients’ treatment eficacy in study group is 92.5% and there are 3 cases of side-efect, side-efect incidence is 7.5%, 37 patients’ treatment eficacy in control group is 78.38% and there are 7 cases of side-efect, side-efect incidence is 18.92%, treatment eficacy in study group is much higher than that in control group and side-efect incidence is much lower in study group; there is a diferential between two groups and such a diferential has statistic value (P< 0.05).Conclusion Mosapride combined with esomeprazole medication is of eficacy in treatment of reflux esophagitis with few side efects; thus, such a treatment method is quite worthwhile to be promoted and applied clinicaly.