中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2015年
3期
465-467
,共3页
朱长艳%李秦莉%肖青%蔡莉%邓淑玲
硃長豔%李秦莉%肖青%蔡莉%鄧淑玲
주장염%리진리%초청%채리%산숙령
围绝经期女性%糖尿病%体质指数%腰臀比%腰围身高比
圍絕經期女性%糖尿病%體質指數%腰臀比%腰圍身高比
위절경기녀성%당뇨병%체질지수%요둔비%요위신고비
peri-menopausal women%diabetes mellitus%body mass index ( BMI)%waist hip ratio ( WHR)%waist to height ratio ( WHtR)
目的：探讨围绝经期女性人体测量参数对2型糖尿病( T2DM)患病风险的预测价值。方法以2011年1月至2014年12月在广州市妇女儿童医疗中心体检中心参与体检并符合纳入标准的637例围绝经期女性为研究对象,进行T2DM患病筛查,测量身高、体重、腰围( WC )、臀围,计算体质指数( BMI )、腰臀比( WHR )和腰围身高比( WHtR )；采用Logistic回归和ROC曲线评估各指标对T2DM患病风险的预测价值。结果有20.3%的调查对象患T2DM；随着BMI(χ2=9.64,P=0.008)、WC(χ2=8.99,P=0.010)、WHR(χ2=18.78,P<0.001)和WHtR(χ2=10.97,P<0.001)反映肥胖程度的增加,T2DM患病率上升,差异均有统计学意义。在控制年龄差异之后的多因素Logistic回归分析结果显示,仅BMI≥28kg/m2( OR=2.61,95%CI：1.22~5.56)和WHR≥0.85(OR=2.35,95%CI：1.43~3.88)与T2DM的发生相关。 ROC测定结果显示,4项指标单独用于预测血糖异常状况的效果均不理想,WHR和WHtR相对较好,ROC曲线下面积(AUC)分别为0.67和0.64,BMI最差,为0.60。结论腹型肥胖指标WHR和WHtR对围绝经期女性T2DM的预测价值优于BMI和WC,其为该时期女性T2DM高危人群的筛查提供了合适的参数。
目的：探討圍絕經期女性人體測量參數對2型糖尿病( T2DM)患病風險的預測價值。方法以2011年1月至2014年12月在廣州市婦女兒童醫療中心體檢中心參與體檢併符閤納入標準的637例圍絕經期女性為研究對象,進行T2DM患病篩查,測量身高、體重、腰圍( WC )、臀圍,計算體質指數( BMI )、腰臀比( WHR )和腰圍身高比( WHtR )；採用Logistic迴歸和ROC麯線評估各指標對T2DM患病風險的預測價值。結果有20.3%的調查對象患T2DM；隨著BMI(χ2=9.64,P=0.008)、WC(χ2=8.99,P=0.010)、WHR(χ2=18.78,P<0.001)和WHtR(χ2=10.97,P<0.001)反映肥胖程度的增加,T2DM患病率上升,差異均有統計學意義。在控製年齡差異之後的多因素Logistic迴歸分析結果顯示,僅BMI≥28kg/m2( OR=2.61,95%CI：1.22~5.56)和WHR≥0.85(OR=2.35,95%CI：1.43~3.88)與T2DM的髮生相關。 ROC測定結果顯示,4項指標單獨用于預測血糖異常狀況的效果均不理想,WHR和WHtR相對較好,ROC麯線下麵積(AUC)分彆為0.67和0.64,BMI最差,為0.60。結論腹型肥胖指標WHR和WHtR對圍絕經期女性T2DM的預測價值優于BMI和WC,其為該時期女性T2DM高危人群的篩查提供瞭閤適的參數。
목적：탐토위절경기녀성인체측량삼수대2형당뇨병( T2DM)환병풍험적예측개치。방법이2011년1월지2014년12월재엄주시부녀인동의료중심체검중심삼여체검병부합납입표준적637례위절경기녀성위연구대상,진행T2DM환병사사,측량신고、체중、요위( WC )、둔위,계산체질지수( BMI )、요둔비( WHR )화요위신고비( WHtR )；채용Logistic회귀화ROC곡선평고각지표대T2DM환병풍험적예측개치。결과유20.3%적조사대상환T2DM；수착BMI(χ2=9.64,P=0.008)、WC(χ2=8.99,P=0.010)、WHR(χ2=18.78,P<0.001)화WHtR(χ2=10.97,P<0.001)반영비반정도적증가,T2DM환병솔상승,차이균유통계학의의。재공제년령차이지후적다인소Logistic회귀분석결과현시,부BMI≥28kg/m2( OR=2.61,95%CI：1.22~5.56)화WHR≥0.85(OR=2.35,95%CI：1.43~3.88)여T2DM적발생상관。 ROC측정결과현시,4항지표단독용우예측혈당이상상황적효과균불이상,WHR화WHtR상대교호,ROC곡선하면적(AUC)분별위0.67화0.64,BMI최차,위0.60。결론복형비반지표WHR화WHtR대위절경기녀성T2DM적예측개치우우BMI화WC,기위해시기녀성T2DM고위인군적사사제공료합괄적삼수。
Objective To explore the predictive values of body anthropometric indices on risk of type 2 diabetes mellitus (T2DM) among peri-menopausal women. Methods The study included 637 peri-menopausal women attending general health screening program during the period of January 2011 to December 2014 in Guangzhou Women and Children Medical Center and meeting the criteria of recruitment. All participants’ body height, weight, waist circumference (WC) and hip circumference were measured to calculate body mass index (BMI), waist hip ratio ( WHR) and waist to height ratio ( WHtR) . Logistic regression analysis and receiver operating characteristics ( ROC) curve were used to predicate the risk of T2DM by each index. Results The prevalence rate of T2DM was 20. 3%. The T2DM morbidity increased with the increasing of BMI (χ2 =9. 64, P=0. 008), WC (χ2 =8. 99,P=0. 010), WHR (χ2 =18. 78,P<0. 001) and WHtR (χ2 =10. 97,P<0. 001), and the difference was statistically significant. After adjusted by age, multivariate logistic regression analysis showed that only BMI≥28kg/m2(OR=2. 61,95%CI:1. 22-5. 56) and WHR≥0. 85 (OR=2. 35,95%CI:1. 43-3. 88) were related with the incidence of T2DM. ROC curve indicated that WHR and WHtR had larger areas under ROC curve, which was 0. 67 and 0. 64, respectively, and AUC of BMI was only 0. 60. Conclusion The predicative value of WHR and WHtR is better than that of BMI and WC. They provide appropriate measurement parameters for screening high risk of T2DM among peri-menopausal women.
