CAJ | 학술논문

目的：调查和分析育龄人群的弓形虫( TOX)感染现状。方法选取500例孕妇和500例未出现TOX感染症状的健康人,分别作为孕妇组和健康组。对所有研究对象的一般资料、宠物接触史及孕妇组研究对象不良妊娠史进行调查和分析。结果健康组、孕妇组近期TOX感染率差异无统计学意义(χ2=1.578,P>0.05)。健康组、孕妇组中有宠物接触史者的近期TOX感染率均显著高于无宠物接触史者(χ2值分别为33.196、20.436,均P<0.05)。孕妇组中具有不良妊娠史者的近期TOX感染率显著高于无不良妊娠史者(χ2=17.837,P<0.05)。孕妇组TOX感染知晓率显著高于健康组(χ2=27.127,P<0.05),年龄(<25岁)、非生物医学相关职业、居住地位于农村地区、学历较低(小学及以下)均是知晓TOX感染的危险因素( OR值分别为1.612、3.287、1.455、2.673,均P<0.05)。结论育龄人群的TOX感染知晓情况受多种人口学因素影响,TOX感染与孕妇不良妊娠史的发生具有相关性,宠物接触史可增加TOX感染风险。
목적：조사화분석육령인군적궁형충( TOX)감염현상。방법선취500례잉부화500례미출현TOX감염증상적건강인,분별작위잉부조화건강조。대소유연구대상적일반자료、총물접촉사급잉부조연구대상불량임신사진행조사화분석。결과건강조、잉부조근기TOX감염솔차이무통계학의의(χ2=1.578,P>0.05)。건강조、잉부조중유총물접촉사자적근기TOX감염솔균현저고우무총물접촉사자(χ2치분별위33.196、20.436,균P<0.05)。잉부조중구유불량임신사자적근기TOX감염솔현저고우무불량임신사자(χ2=17.837,P<0.05)。잉부조TOX감염지효솔현저고우건강조(χ2=27.127,P<0.05),년령(<25세)、비생물의학상관직업、거주지위우농촌지구、학력교저(소학급이하)균시지효TOX감염적위험인소( OR치분별위1.612、3.287、1.455、2.673,균P<0.05)。결론육령인군적TOX감염지효정황수다충인구학인소영향,TOX감염여잉부불량임신사적발생구유상관성,총물접촉사가증가TOX감염풍험。
Objective To investigate and analyze the current situation of Toxoplasma ( TOX ) infection in reproductive population. Methods Five hundred pregnant women and 500 cases of healthy people without any symptoms of TOX infection were selected and grouped into pregnant group and health group. The general information and the history of exposure to pets of all the included objects, and the adverse pregnancy history of pregnant women in the pregnancy group were investigated and compared. Results There was no significant difference in TOX infection rate between health group and pregnant group (χ2 =1. 578, P >0. 05). The recent TOX infection rate of women who had pet exposure history in both groups was significantly higher than that without pet exposure history (χ2 value was 33. 196 and 20. 436, respectively, both P<0. 05). The recent TOX infection rate of women who had history of adverse pregnancy in pregnant group was significantly higher than that without history of adverse pregnancy (χ2 =17. 837,P<0. 05). The awareness rate of TOX infection was significantly higher in pregnant group than in health group (χ2 =27. 127,P<0. 05). Age ( < 25), biomedical related occupation, located in rural areas, low education (primary school and below) were risk factors of TOX infection (OR value was 1. 612, 3. 287, 1. 455 and 2. 673, respectively, all P <0. 05). Conclusion The awareness of TOX infection of reproductive population is affected by various demographic factors. TOX infection is correlated with the occurrence of adverse pregnancy outcomes in pregnant women, and the history of exposure to pets will increase the risk of TOX infection.