中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
16期
141-143
,共3页
卡托普利%美托洛尔%慢性充血性心力衰竭
卡託普利%美託洛爾%慢性充血性心力衰竭
잡탁보리%미탁락이%만성충혈성심력쇠갈
Captopril%Metoprolol%Chronic congestive heart failure
目的：探讨卡托普利联合美托洛尔治疗慢性充血性心力衰竭的临床效果。方法选取本院2012年6月~2013年6月收治的102例慢性充血性心力衰竭患者作为研究对象，按照随机数字表法分为观察组和对照组，各51例，对照组给予常规治疗，观察组在对照组的基础上给予卡托普利联合美托洛尔治疗，比较两组的治疗效果，治疗前后的收缩压（SBP）、舒张压（DBP）、心率（HR）、6 min步行距离试验、肾功能、电解质及不良反应发生率。结果观察组的总有效率为92.16%，显著高于对照组的72.55%，差异有统计学意义（P<0.05）。观察组治疗后的SPB、DBP、HR、及6 min步行距离试验显著优于治疗前及对照组治疗后，差异有统计学意义（P<0.05）。观察组的不良反应发生率为7.84%，显著低于对照组的23.53%，差异有统计学意义（P<0.05）。结论卡托普利联合美托洛尔治疗慢性充血性心力衰竭效果显著，能够降低血压及不良反应发生率，值得临床推广应用。
目的：探討卡託普利聯閤美託洛爾治療慢性充血性心力衰竭的臨床效果。方法選取本院2012年6月~2013年6月收治的102例慢性充血性心力衰竭患者作為研究對象，按照隨機數字錶法分為觀察組和對照組，各51例，對照組給予常規治療，觀察組在對照組的基礎上給予卡託普利聯閤美託洛爾治療，比較兩組的治療效果，治療前後的收縮壓（SBP）、舒張壓（DBP）、心率（HR）、6 min步行距離試驗、腎功能、電解質及不良反應髮生率。結果觀察組的總有效率為92.16%，顯著高于對照組的72.55%，差異有統計學意義（P<0.05）。觀察組治療後的SPB、DBP、HR、及6 min步行距離試驗顯著優于治療前及對照組治療後，差異有統計學意義（P<0.05）。觀察組的不良反應髮生率為7.84%，顯著低于對照組的23.53%，差異有統計學意義（P<0.05）。結論卡託普利聯閤美託洛爾治療慢性充血性心力衰竭效果顯著，能夠降低血壓及不良反應髮生率，值得臨床推廣應用。
목적：탐토잡탁보리연합미탁락이치료만성충혈성심력쇠갈적림상효과。방법선취본원2012년6월~2013년6월수치적102례만성충혈성심력쇠갈환자작위연구대상，안조수궤수자표법분위관찰조화대조조，각51례，대조조급여상규치료，관찰조재대조조적기출상급여잡탁보리연합미탁락이치료，비교량조적치료효과，치료전후적수축압（SBP）、서장압（DBP）、심솔（HR）、6 min보행거리시험、신공능、전해질급불량반응발생솔。결과관찰조적총유효솔위92.16%，현저고우대조조적72.55%，차이유통계학의의（P<0.05）。관찰조치료후적SPB、DBP、HR、급6 min보행거리시험현저우우치료전급대조조치료후，차이유통계학의의（P<0.05）。관찰조적불량반응발생솔위7.84%，현저저우대조조적23.53%，차이유통계학의의（P<0.05）。결론잡탁보리연합미탁락이치료만성충혈성심력쇠갈효과현저，능구강저혈압급불량반응발생솔，치득림상추엄응용。
Objective To explore the clinical effect of captopril combined with metoprolol in the treatment of chronic congestive heart failure. Methods 102 cases with chronic congestive heart failure in our hospital from June 2012 to 2013 were selected and divided into the observation group and the control group according to the method of random digits table,51 cases in each group.The control group was given conventional treatment,the observation group was treat-ed with captopril combined with metoprolol on the basis of the control group.The treatment effect,systolic blood pres-sure (SBP),diastolic blood pressure(DBP),heart rate(HR),6min walk test,renal function,electrolyte before and after treat-ment and the incidence of adverse reaction in two groups was compared respectively. Results The total effective rate of the observation group was 92.16%,which was higher than 72.55% of the control group,with significant difference (P<0.05).The level of SPB,DBP,HR and 6 min walk test in the observation group after treatment was better than that before treatment and the control group after treatment,with significant difference (P<0.05).The incidence of adverse reaction in the observation group was 7.84%,which was lower than 23.53% in the control group,with significant difference(P<0.05). Conclusion The effect of captopril combined with metoprolol in the treatment of chronic congestive heart failure is sig-nificant,which can reduce reduce the blood pressure and the incidence of adverse reaction,it is worthy of clinical pro-motion and application.
