中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2015年
3期
566-567,578
,共3页
炎琥宁%α干扰素%小儿%急性上呼吸道感染
炎琥寧%α榦擾素%小兒%急性上呼吸道感染
염호저%α간우소%소인%급성상호흡도감염
Yanhuning%α interferon%children%acute upper respiratory tract infection
目的：探讨炎琥宁联合α干扰素治疗小儿急性上呼吸道感染临床治疗效果和不良反应。方法选择武义县妇幼保健院2013年7月至2014年5月收治的急性上呼吸道感染小儿患者204例,根据治疗方法将所有患儿分为对照组和治疗组,对照组105例,应用α干扰素治疗；治疗组99例,在对照组基础上联合炎琥宁注射液治疗,比较两组治疗效果。结果治疗组患儿治愈率显著高于对照组(χ2=5.28,P<0.05),且治疗组患儿平均治疗时间显著短于对照组(t=6.39,P<0.05)。治疗组退热时间、咳嗽消失时间、鼻塞流涕消失时间和白细胞计数恢复时间均显著低于对照组(t值分别为5.44、6.17、4.93、5.06,均P<0.05)。两组治疗后平均体温均低于治疗前,差异具有统计学意义(t值分别为9.37、10.26,均P<0.05)。治疗组治疗后平均体温显著低于对照组(t=6.88,P<0.05)。两组患者不良反应比较无显著性差异(χ2=1.04,P>0.05)。结论炎琥宁联合α干扰素治疗小儿急性上呼吸道感染临床效果较好,能够显著缩短患者治疗时间,值得临床推广使用。
目的：探討炎琥寧聯閤α榦擾素治療小兒急性上呼吸道感染臨床治療效果和不良反應。方法選擇武義縣婦幼保健院2013年7月至2014年5月收治的急性上呼吸道感染小兒患者204例,根據治療方法將所有患兒分為對照組和治療組,對照組105例,應用α榦擾素治療；治療組99例,在對照組基礎上聯閤炎琥寧註射液治療,比較兩組治療效果。結果治療組患兒治愈率顯著高于對照組(χ2=5.28,P<0.05),且治療組患兒平均治療時間顯著短于對照組(t=6.39,P<0.05)。治療組退熱時間、咳嗽消失時間、鼻塞流涕消失時間和白細胞計數恢複時間均顯著低于對照組(t值分彆為5.44、6.17、4.93、5.06,均P<0.05)。兩組治療後平均體溫均低于治療前,差異具有統計學意義(t值分彆為9.37、10.26,均P<0.05)。治療組治療後平均體溫顯著低于對照組(t=6.88,P<0.05)。兩組患者不良反應比較無顯著性差異(χ2=1.04,P>0.05)。結論炎琥寧聯閤α榦擾素治療小兒急性上呼吸道感染臨床效果較好,能夠顯著縮短患者治療時間,值得臨床推廣使用。
목적：탐토염호저연합α간우소치료소인급성상호흡도감염림상치료효과화불량반응。방법선택무의현부유보건원2013년7월지2014년5월수치적급성상호흡도감염소인환자204례,근거치료방법장소유환인분위대조조화치료조,대조조105례,응용α간우소치료；치료조99례,재대조조기출상연합염호저주사액치료,비교량조치료효과。결과치료조환인치유솔현저고우대조조(χ2=5.28,P<0.05),차치료조환인평균치료시간현저단우대조조(t=6.39,P<0.05)。치료조퇴열시간、해수소실시간、비새류체소실시간화백세포계수회복시간균현저저우대조조(t치분별위5.44、6.17、4.93、5.06,균P<0.05)。량조치료후평균체온균저우치료전,차이구유통계학의의(t치분별위9.37、10.26,균P<0.05)。치료조치료후평균체온현저저우대조조(t=6.88,P<0.05)。량조환자불량반응비교무현저성차이(χ2=1.04,P>0.05)。결론염호저연합α간우소치료소인급성상호흡도감염림상효과교호,능구현저축단환자치료시간,치득림상추엄사용。
Objective To explore the clinical therapeutic effects and adverse reactions of Yanhuning combined with α interferon on the treatment of children with acute upper respiratory tract infection. Methods Totally 204 children with acute upper respiratory tract infection were selected in Maternal and Child Health Hospital of Wuyi County from July 2013 to May 2014. They were divided into control group (n=105) receiving α interferon and treatment group (n=99) accepting Yanhuning injection based on the therapy for the control group. The clinical therapeutic effects were observed and compared between two groups. Results The cure rate of the treatment group was significantly higher than that in the control group (χ2 =5. 28,P<0. 05), and the average treatment course was significantly shorter in the treatment group (t =6. 39,P <0. 05). The fever disappearance, cough disappearance, congestion disappearance and white blood cell count recovery were sooner in the treatment group than the control group (t value was 5. 44, 6. 17, 4. 93 and 5. 06, respectively, all P<0. 05). After treatment the average temperature of two groups was significantly lower than that before treatment (t value was 9. 37 and 10. 26, respectively, both P<0. 05), and the average temperature of the treatment group was significantly lower than the control group (t=6. 88,P<0. 05). There was no significant difference in adverse reactions between two groups (χ2 =1. 04,P>0. 05). Conclusion Yanhuning combined with α interferon has good effect on the treatment of children with acute upper respiratory tract infection, which can significantly shorten the treatment course and is worthy of clinical application.
