中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2015年
3期
511-514
,共4页
陈丽琴%吴越慧%朱聪茶%吴秋芬
陳麗琴%吳越慧%硃聰茶%吳鞦芬
진려금%오월혜%주총다%오추분
卵巢子宫内膜异位症囊肿%腹腔镜%促性腺激素释放激素激动剂%血府逐瘀胶囊
卵巢子宮內膜異位癥囊腫%腹腔鏡%促性腺激素釋放激素激動劑%血府逐瘀膠囊
란소자궁내막이위증낭종%복강경%촉성선격소석방격소격동제%혈부축어효낭
ovarian endometrial implantation cyst ( OEC)%laparoscope%GnRHa%Xuefuzhuyu Capsule
目的：探讨血府逐瘀胶囊在腹腔镜联合促性腺激素释放激素激动剂( GnRHa )治疗卵巢子宫内膜异位症囊肿( OEC)中的作用。方法将48名OEC患者按照随机数表法平均分为对照组和治疗组。对照组接受腹腔镜联合GnRHa治疗,治疗组则在对照组治疗基础上加用血府逐瘀胶囊进行治疗。观察并比较两组患者的临床完全缓解率、复发率、痛经及性交痛VAS评分,以及血清中卵泡刺激素( FSH)、黄体生成素( LH)、雌二醇( E2)和孕激素( P)的水平。结果治疗组临床完全缓解率显著高于对照组(χ2=5.107,P<0.05),而复发率显著低于对照组(χ2=3.414,P<0.05)。治疗后两组痛经和性交痛VAS评分比较差异均有统计学意义(t值分别为3.114、2.125,均P<0.05),治疗后两组LH、FSH、P、E2水平比较差异均有统计学意义(t值分别为3.117、4.182、2.960、2.544,均P<0.05)。结论血府逐瘀胶囊适用于辅助腹腔镜联合GnRHa疗法OEC,有利于增强临床疗效。
目的：探討血府逐瘀膠囊在腹腔鏡聯閤促性腺激素釋放激素激動劑( GnRHa )治療卵巢子宮內膜異位癥囊腫( OEC)中的作用。方法將48名OEC患者按照隨機數錶法平均分為對照組和治療組。對照組接受腹腔鏡聯閤GnRHa治療,治療組則在對照組治療基礎上加用血府逐瘀膠囊進行治療。觀察併比較兩組患者的臨床完全緩解率、複髮率、痛經及性交痛VAS評分,以及血清中卵泡刺激素( FSH)、黃體生成素( LH)、雌二醇( E2)和孕激素( P)的水平。結果治療組臨床完全緩解率顯著高于對照組(χ2=5.107,P<0.05),而複髮率顯著低于對照組(χ2=3.414,P<0.05)。治療後兩組痛經和性交痛VAS評分比較差異均有統計學意義(t值分彆為3.114、2.125,均P<0.05),治療後兩組LH、FSH、P、E2水平比較差異均有統計學意義(t值分彆為3.117、4.182、2.960、2.544,均P<0.05)。結論血府逐瘀膠囊適用于輔助腹腔鏡聯閤GnRHa療法OEC,有利于增彊臨床療效。
목적：탐토혈부축어효낭재복강경연합촉성선격소석방격소격동제( GnRHa )치료란소자궁내막이위증낭종( OEC)중적작용。방법장48명OEC환자안조수궤수표법평균분위대조조화치료조。대조조접수복강경연합GnRHa치료,치료조칙재대조조치료기출상가용혈부축어효낭진행치료。관찰병비교량조환자적림상완전완해솔、복발솔、통경급성교통VAS평분,이급혈청중란포자격소( FSH)、황체생성소( LH)、자이순( E2)화잉격소( P)적수평。결과치료조림상완전완해솔현저고우대조조(χ2=5.107,P<0.05),이복발솔현저저우대조조(χ2=3.414,P<0.05)。치료후량조통경화성교통VAS평분비교차이균유통계학의의(t치분별위3.114、2.125,균P<0.05),치료후량조LH、FSH、P、E2수평비교차이균유통계학의의(t치분별위3.117、4.182、2.960、2.544,균P<0.05)。결론혈부축어효낭괄용우보조복강경연합GnRHa요법OEC,유리우증강림상료효。
Objective To explore the clinical efficacy of Xuefuzhuyu Capsule in treatment of OEC by combining laparoscope with GnRHa. Methods Forty-eight cases with OEC were evenly divided into control group and treatment group according to random number table. The control group received treatment of laparoscope and GnRHa, while the treatment group received Xuefuzhuyu Capsule therapy based on the treatment for the control group. Complete remission rate, recurrence rate, VAS scores of menstrual pain and dyspareunia, serum levels of FSH, LH, P and E2 were assessed and compared between two groups. Results The complete remission rate of the treatment group was significantly higher than that of the control group (χ2 =5. 107,P<0. 05), but the recurrence rate was significantly lower in the treatment group (χ2 =3. 414, P <0. 05). VAS scores of menstrual pain and dyspareunia were significantly different between two groups after treatment (t value was 3. 114 and 2. 125, respectively, both P<0. 05), and the differences in serum levels of LH, FSH, E2 and P were significant between two groups (t value was 3. 117, 4. 182, 2. 960 and 2. 544, respectively, all P <0. 05). Conclusion Xuefuzhuyu Capsule is applicable in treatment of OEC to assist laparoscope and GnRHa, and it improves clinical efficacy.
