CAJ | 학술논문

目的：初步探讨对人类获得性免疫缺陷病毒感染者或艾滋病患者（human immunodeficiency virus or acquired immune defi-ciency syndrome ，HIV ／AIDS）口腔表征的影响因素，为艾滋病口腔表征的诊治提供资料和科学依据。方法对某省在押71例男性 HIV 感染者／AIDS 患者进行横断面调查：临床检查＋问卷调查，了解其口腔表征、实验室指标及人口学特征等，分析对口腔表征的影响因素。结果71例男性患者中，30～39岁，共32例（45．1％），经静脉吸毒传播28例（39．4％）。CD4＋计数较高，中位数为279．00·mm －3，IQR：263．00～409．00·mm －3。与 HIV ／AIDS 相关的口腔表征较少。口腔卫生维护意识、行为评分较高，其中位数为8分，IQR：7～9分。多因素 Logistic 回归分析显示：CD4＋＜350·mm －3（χ2＝13．170，OR ＝101．220，P≤0．010）、口腔卫生总分中（χ2＝4．992，OR ＝14．451，P≤0．050）、差（χ2＝11．374，OR ＝161．066，P≤0．010）及感染时间≥40个月（χ2＝5．377，OR ＝7．312，P≤0．050）均对口腔表征的影响有统计学意义。结论HIV 感染者／AIDS 患者的 CD4＋计数越高，口腔卫生状况越好，感染时间越短，其 HIV ／AIDS 相关口腔表征的发生率越低。
목적：초보탐토대인류획득성면역결함병독감염자혹애자병환자（human immunodeficiency virus or acquired immune defi-ciency syndrome ，HIV ／AIDS）구강표정적영향인소，위애자병구강표정적진치제공자료화과학의거。방법대모성재압71례남성 HIV 감염자／AIDS 환자진행횡단면조사：림상검사＋문권조사，료해기구강표정、실험실지표급인구학특정등，분석대구강표정적영향인소。결과71례남성환자중，30～39세，공32례（45．1％），경정맥흡독전파28례（39．4％）。CD4＋계수교고，중위수위279．00·mm －3，IQR：263．00～409．00·mm －3。여 HIV ／AIDS 상관적구강표정교소。구강위생유호의식、행위평분교고，기중위수위8분，IQR：7～9분。다인소 Logistic 회귀분석현시：CD4＋＜350·mm －3（χ2＝13．170，OR ＝101．220，P≤0．010）、구강위생총분중（χ2＝4．992，OR ＝14．451，P≤0．050）、차（χ2＝11．374，OR ＝161．066，P≤0．010）급감염시간≥40개월（χ2＝5．377，OR ＝7．312，P≤0．050）균대구강표정적영향유통계학의의。결론HIV 감염자／AIDS 환자적 CD4＋계수월고，구강위생상황월호，감염시간월단，기 HIV ／AIDS 상관구강표정적발생솔월저。
Objective To explore the influence factors on oral characterizations of HIV /AIDS patients to provide a basis for the treat-ment.Methods A cross-sectional survey was performed on 71 HIV /AIDS patients who were in custody.Oral lesions were diagnosed by a detailed physical examination.Demographic details and oral health maintenance were collected by a questionnaire,and laboratory in-dexes were obtained from medical records.Results Among the 71 male HIV /AIDS patients,most were in the age of 30 ~39 years old (32,0.451),the most common mode of transmission was injected drug use(28,0.394).The median of CD4 +count was 279.00· mm -3 (IQR:263.00 ~409.00·mm -3 ).Oral lesions of HIV /AIDS were not common.The median score of oral health maintenance was 8(IQR:7 ~9).The multivariate Logistic analysis showed that CD4 + <350·mm -3 (χ2 = 13.170,OR = 101.220,P≤0.010).The middle score of oral health (maintenance χ2 =4.992,OR =14.451,P≤0.05)and bad (χ2 =11.374,OR =161.066,P≤0.01), and the infected period ≥40 months (χ2 =5.377,OR =7.312,P≤0.050)were significantly related to oral characterizations.Con-clusions The higher the CD4 +count,the better the oral health and the shorter the infected period,which can lead to the lower inci-dence of oral characterizations.