CAJ | 학술논문

目的：分析神经心理学测试及事件相关电位N400对抑郁症患者治疗的临床价值。方法随机选取该院于2013年4月-2014年4月收治的30例抑郁症患者相关资料进行分析，将其设置为实验组，选择同期入院的30例非抑郁症患者作为对照组，患者入院后均进行神经心理学测试，采用MEB-9140K诱发电位仪检测事件相关电位B400，比较两组相关指标。结果实验组发病后抑郁评分为(33.87±5.62)分、焦虑评分为(42.87±6.45)分，低于对照组(P<0.05)；实验组发病1 d平均波幅为(4.5±1.4)V、发病15 d平均波幅为(6.1±1.2)V、发病30 d平均波幅为(7.4±0.9)V，显著低于对照组(P<0.05)。结论抑郁症患者心理波动性比较大，且其事件相关电位N400的潜伏期在治疗前和治疗过程中有所延长，N400的平均波幅在病床不同时期有所下降。
목적：분석신경심이학측시급사건상관전위N400대억욱증환자치료적림상개치。방법수궤선취해원우2013년4월-2014년4월수치적30례억욱증환자상관자료진행분석，장기설치위실험조，선택동기입원적30례비억욱증환자작위대조조，환자입원후균진행신경심이학측시，채용MEB-9140K유발전위의검측사건상관전위B400，비교량조상관지표。결과실험조발병후억욱평분위(33.87±5.62)분、초필평분위(42.87±6.45)분，저우대조조(P<0.05)；실험조발병1 d평균파폭위(4.5±1.4)V、발병15 d평균파폭위(6.1±1.2)V、발병30 d평균파폭위(7.4±0.9)V，현저저우대조조(P<0.05)。결론억욱증환자심리파동성비교대，차기사건상관전위N400적잠복기재치료전화치료과정중유소연장，N400적평균파폭재병상불동시기유소하강。
Objective To investigate the clinical significance of neuropsychological tests and N400 event-related potentials in the treatment of patients with depression. Methods 30 patients with depression and 30 patients without depression admitted to our hos-pital from 2013 April to 2014 April during the same period were selected as the experimental group and control group respective-ly. All the 60 patients received neuropsychological tests and event-related potentials N400 detection by MEB -9140K after ad-mission. Relevant indicators were compared. Results The experimental group after the onset of depression score was (33.87±5.62), anxiety score was (42.87±6.45) points lower than the control group (P<0.05); the experimental group, the average amplitude of the onset of one day (4.5±1.4) V , the average amplitude of the onset of 15 days (6.1±1.2) V, the average amplitude of the onset of 30 days (7.4±0.9) V, significantly lower than the control group (P<0.05). Conclusion Volatility of patients with mental depression volatility is relatively large, and the event-related potential N400 latency period has been extended in the course of pre-treatment and treatment, the average amplitude of N400 decline in bed at different times.