中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2015年
19期
23-24,25
,共3页
二甲双胍片%糖尿病前期%临床疗效
二甲雙胍片%糖尿病前期%臨床療效
이갑쌍고편%당뇨병전기%림상료효
Metformin Tablets%Pre-diabetes%Clinical effect
目的：研究二甲双胍在糖尿病前期中的应用价值。方法：选取2011年12月-2013年12月笔者所在医院收治的68例糖尿病前期患者，按照随机数字表法将其分为两组，每组34例。对照组采用常规运动干预、饮食控制治疗，观察组在对照组基础上给予二甲双胍片治疗，比较两组患者的治疗效果，并了解观察组患者是否发生不良反应。结果：观察组显效23例，有效10例，总有效率为97.1%；对照组显效18例，有效6例，总有效率为76.5%，观察组总有效率优于对照组，差异有统计学意义(P<0.05)。观察组中，1例患者出现不良反应，发生率为2.9%，对照组中无患者出现不良反应，两组比较差异无统计学意义(P>0.05)。观察组中2例患者发生糖尿病，发生率为5.9%，对照组中8例患者发生糖尿病，发生率为23.5%，观察组糖尿病发生率低于对照组，差异有统计学意义(P<0.05)。结论：通过采用二甲双胍对糖尿病前期患者进行治疗，可以有效改善患者血糖水平，值得临床推广应用。
目的：研究二甲雙胍在糖尿病前期中的應用價值。方法：選取2011年12月-2013年12月筆者所在醫院收治的68例糖尿病前期患者，按照隨機數字錶法將其分為兩組，每組34例。對照組採用常規運動榦預、飲食控製治療，觀察組在對照組基礎上給予二甲雙胍片治療，比較兩組患者的治療效果，併瞭解觀察組患者是否髮生不良反應。結果：觀察組顯效23例，有效10例，總有效率為97.1%；對照組顯效18例，有效6例，總有效率為76.5%，觀察組總有效率優于對照組，差異有統計學意義(P<0.05)。觀察組中，1例患者齣現不良反應，髮生率為2.9%，對照組中無患者齣現不良反應，兩組比較差異無統計學意義(P>0.05)。觀察組中2例患者髮生糖尿病，髮生率為5.9%，對照組中8例患者髮生糖尿病，髮生率為23.5%，觀察組糖尿病髮生率低于對照組，差異有統計學意義(P<0.05)。結論：通過採用二甲雙胍對糖尿病前期患者進行治療，可以有效改善患者血糖水平，值得臨床推廣應用。
목적：연구이갑쌍고재당뇨병전기중적응용개치。방법：선취2011년12월-2013년12월필자소재의원수치적68례당뇨병전기환자，안조수궤수자표법장기분위량조，매조34례。대조조채용상규운동간예、음식공제치료，관찰조재대조조기출상급여이갑쌍고편치료，비교량조환자적치료효과，병료해관찰조환자시부발생불량반응。결과：관찰조현효23례，유효10례，총유효솔위97.1%；대조조현효18례，유효6례，총유효솔위76.5%，관찰조총유효솔우우대조조，차이유통계학의의(P<0.05)。관찰조중，1례환자출현불량반응，발생솔위2.9%，대조조중무환자출현불량반응，량조비교차이무통계학의의(P>0.05)。관찰조중2례환자발생당뇨병，발생솔위5.9%，대조조중8례환자발생당뇨병，발생솔위23.5%，관찰조당뇨병발생솔저우대조조，차이유통계학의의(P<0.05)。결론：통과채용이갑쌍고대당뇨병전기환자진행치료，가이유효개선환자혈당수평，치득림상추엄응용。
Objective:To study the applied value of Metformin in the treatment of pre-diabetes.Method:68 cases of patients with pre-diabetes in our hospital from December 2011 to December 2013 were selected,they were randomly divided into two groups,34 cases in each group.The control group was given routine exercise intervention,diet therapy,the observation group on the basis of the control group was given metformin treatment,the effect of two groups were compared,and the adverse reaction of the observation group was observed.Result:In the observation group,23 cases had marked effect,10 cases were effect, the total effective rate was 97.1%.The control group,18 cases had marked effect,8 cases were effect,the total effective rate was 76.5%,the total effective rate of the observation group was higher than that of the control group,there was statistical significance(P<0.05).The incidence rate of the observation group was 2.9%, no adverse reactions in patients of the control group,there was no statistical significance(P<0.05).There were 2 cases of patients with diabetes in the observation group,the incidence rate of the observation group was 5.9%,the control group was 20.6%,there was statistical significance(P<0.05).Conclusion:By adopting of pre-diabetes patients were treated with Metformin,can effectively improve the patients blood glucose levels,it is worthy of clinical application.
