中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2015年
19期
16-17
,共2页
刘凌霞%成景山%莫芳梅%罗爱红
劉凌霞%成景山%莫芳梅%囉愛紅
류릉하%성경산%막방매%라애홍
2型糖尿病%非酒精性脂肪肝%血脂异常%胰岛素抵抗
2型糖尿病%非酒精性脂肪肝%血脂異常%胰島素牴抗
2형당뇨병%비주정성지방간%혈지이상%이도소저항
Type 2 diabetes mellitus%Nonalcoholic fatty liver%Dyslipidemia%Insulin resistance
目的：探讨2型糖尿病(T2DM)合并非酒精性脂肪肝(NAFL)与血脂异常、胰岛素抵抗的关系。方法：选择57例T2DM合并NAFL患者和55例单纯T2DM患者分别作为观察组和对照组，比较两组患者血脂指标、血糖指标、胰岛素抵抗情况，并进行Logistic多元回归分析。结果：观察组患者TG、FIns、2 h Ins、HOMA-IR均高于对照组，HDL-C则低于对照组(P<0.05)。两组TC、LDL-C、FPG、2 h PG、HbA1c等比较差异均无统计学意义(P>0.05)。NAFL与TG、HDL-C、HOMA-IR独立相关。结论：T2DM合并NAFL存在明显血脂异常和胰岛素抵抗情况。
目的：探討2型糖尿病(T2DM)閤併非酒精性脂肪肝(NAFL)與血脂異常、胰島素牴抗的關繫。方法：選擇57例T2DM閤併NAFL患者和55例單純T2DM患者分彆作為觀察組和對照組，比較兩組患者血脂指標、血糖指標、胰島素牴抗情況，併進行Logistic多元迴歸分析。結果：觀察組患者TG、FIns、2 h Ins、HOMA-IR均高于對照組，HDL-C則低于對照組(P<0.05)。兩組TC、LDL-C、FPG、2 h PG、HbA1c等比較差異均無統計學意義(P>0.05)。NAFL與TG、HDL-C、HOMA-IR獨立相關。結論：T2DM閤併NAFL存在明顯血脂異常和胰島素牴抗情況。
목적：탐토2형당뇨병(T2DM)합병비주정성지방간(NAFL)여혈지이상、이도소저항적관계。방법：선택57례T2DM합병NAFL환자화55례단순T2DM환자분별작위관찰조화대조조，비교량조환자혈지지표、혈당지표、이도소저항정황，병진행Logistic다원회귀분석。결과：관찰조환자TG、FIns、2 h Ins、HOMA-IR균고우대조조，HDL-C칙저우대조조(P<0.05)。량조TC、LDL-C、FPG、2 h PG、HbA1c등비교차이균무통계학의의(P>0.05)。NAFL여TG、HDL-C、HOMA-IR독립상관。결론：T2DM합병NAFL존재명현혈지이상화이도소저항정황。
Objective:To explore the relationship between dyslipidemia and insulin resistance in type 2 diabetes mellitus associated with nonalcoholic fatty liver.Method:57 patients of T2DM with NAFL and 55 patients of simple T2DM were selected as the observation group and the control group.The serum lipids, blood sugar and insulin resistance in two group were compared,logistic multiple regression analysis was use to analyze.Result:The triglyceride,fasting insulin, 2 h postprandial insulin and HOMA-IR in the observation group were significantly higher than those in the control group,the high density lipoprotein cholesterol was significantly lower than the control group(P<0.05).The total cholesterol,low density lipoprotein cholesterin,fasting blood glucose,2 h postprandial glucose and hemoglobin Alc were not statistically signigicant between two groups(P>0.05).The triglyceride,high density lipoprotein cholestetin and HOMA-IR were the independent influence factors of NAFL.Conclusion:There are obvious dyslipidemia and insulin resistance in T2DM with NAFL patients.
