医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2015年
17期
33-33,34
,共2页
猪%内源性逆转录病毒%分子
豬%內源性逆轉錄病毒%分子
저%내원성역전록병독%분자
The pig%Endogenous retroviruses%Molecular
PERV是一种整合到猪基因组中的逆转录病毒,在异种移植、生物人工肝等技术中可能感染人。PERV存在于猪的各种组织器官中,并可体外感染人源细胞及细胞系,其复制、表达及对受体细胞的感染能力均与其分子结构相关,本文就PERV的分子方面进行综述,以期对PERV的进一步研究有所帮助。
PERV是一種整閤到豬基因組中的逆轉錄病毒,在異種移植、生物人工肝等技術中可能感染人。PERV存在于豬的各種組織器官中,併可體外感染人源細胞及細胞繫,其複製、錶達及對受體細胞的感染能力均與其分子結構相關,本文就PERV的分子方麵進行綜述,以期對PERV的進一步研究有所幫助。
PERV시일충정합도저기인조중적역전록병독,재이충이식、생물인공간등기술중가능감염인。PERV존재우저적각충조직기관중,병가체외감염인원세포급세포계,기복제、표체급대수체세포적감염능력균여기분자결구상관,본문취PERV적분자방면진행종술,이기대PERV적진일보연구유소방조。
Passing PERV is an integrated in to the pig genome retroviruses, in xenotransplantation, biological artificial liver technology can infect people. Passing PERV exists in pigs of all kinds of tissues and organs, and can infection anthropogenic cells and cell lines in vitro, the replication, expression and infection ability of receptor cells are related to its molecular structure, molecular aspects were summarized in this paper, the passing PERV, in order to help the further study of the passing PERV.