国际病毒学杂志
國際病毒學雜誌
국제병독학잡지
INTERNATIONAL JOURNAL OF VIROLOGY
2015年
3期
194-196
,共3页
右美托咪定%布托啡诺%病毒性脑炎%镇痛镇静
右美託咪定%佈託啡諾%病毒性腦炎%鎮痛鎮靜
우미탁미정%포탁배낙%병독성뇌염%진통진정
Dexmedetomidine%Bhutto butorphanol%Viral encephalitis%Analgesia and sedation
目的 分析病毒性脑炎患者应用联合右美托咪定及布托啡诺治疗的临床效果.方法 将64例病毒性脑炎患者随机分为对照组及观察组,每组32例.以接受右美托咪定镇痛治疗者为对照组,以联合接受右美托咪定及布托啡诺镇痛治疗者为观察组,对比两组接受治疗后的镇痛镇静效果及药物副作用发生率.结果 观察组接受治疗后止痛起效时间、镇静起效时间、止痛持续时间及镇静持续时间分别为(10.12±2.77) min、(17.71 ±3.51)min、(766.61 ±86.12) min及(653.55±98.32) min明显短于对照组的(13.61 ±3.61)min、(21.67 ±3.26) min、(731.21 ±78.24) min及(610.27 ±86.38) min(P<0.05);同时治疗前两组生活质量各项评分比较未见统计学差异(P>0.05),经治疗后观察组生活质量各项评分改善较对照组更为明显(P<0.05).此外两组药物副作用发生率比较未见统计学差异(P>0.05).结论 联合右美托咪定及布托啡诺治疗可显著提高病毒性脑炎患者的镇痛镇静效果.
目的 分析病毒性腦炎患者應用聯閤右美託咪定及佈託啡諾治療的臨床效果.方法 將64例病毒性腦炎患者隨機分為對照組及觀察組,每組32例.以接受右美託咪定鎮痛治療者為對照組,以聯閤接受右美託咪定及佈託啡諾鎮痛治療者為觀察組,對比兩組接受治療後的鎮痛鎮靜效果及藥物副作用髮生率.結果 觀察組接受治療後止痛起效時間、鎮靜起效時間、止痛持續時間及鎮靜持續時間分彆為(10.12±2.77) min、(17.71 ±3.51)min、(766.61 ±86.12) min及(653.55±98.32) min明顯短于對照組的(13.61 ±3.61)min、(21.67 ±3.26) min、(731.21 ±78.24) min及(610.27 ±86.38) min(P<0.05);同時治療前兩組生活質量各項評分比較未見統計學差異(P>0.05),經治療後觀察組生活質量各項評分改善較對照組更為明顯(P<0.05).此外兩組藥物副作用髮生率比較未見統計學差異(P>0.05).結論 聯閤右美託咪定及佈託啡諾治療可顯著提高病毒性腦炎患者的鎮痛鎮靜效果.
목적 분석병독성뇌염환자응용연합우미탁미정급포탁배낙치료적림상효과.방법 장64례병독성뇌염환자수궤분위대조조급관찰조,매조32례.이접수우미탁미정진통치료자위대조조,이연합접수우미탁미정급포탁배낙진통치료자위관찰조,대비량조접수치료후적진통진정효과급약물부작용발생솔.결과 관찰조접수치료후지통기효시간、진정기효시간、지통지속시간급진정지속시간분별위(10.12±2.77) min、(17.71 ±3.51)min、(766.61 ±86.12) min급(653.55±98.32) min명현단우대조조적(13.61 ±3.61)min、(21.67 ±3.26) min、(731.21 ±78.24) min급(610.27 ±86.38) min(P<0.05);동시치료전량조생활질량각항평분비교미견통계학차이(P>0.05),경치료후관찰조생활질량각항평분개선교대조조경위명현(P<0.05).차외량조약물부작용발생솔비교미견통계학차이(P>0.05).결론 연합우미탁미정급포탁배낙치료가현저제고병독성뇌염환자적진통진정효과.
Objective To analyze the clinical effect for patients with viral encephalitis combined application of dexmedetomidine and Bhutto butorphanol treatment.Methods 64 cases of viral encephalitis were randomly divided into control group and observation group,32 cases in each group.Control group was accepted the dexmedetomidine analgesic therapy.Observation group was accepted Dexmedetomidine and Bhutto butorphanol analgesia treatment.Sedative and analgesic effects of treatment was analyzed.Results Analgesic effect time,sedative effect time,duration of analgesic time,duration of sedative time of observation group was shorter than that of control group (P < 0.05).observation group quality of life scores improved more significantly than that of the control group (P < 0.05).In addition,two groups of drug side effects and compare the incidence rate was not statistically different (P > 0.05).Conclusions The combination of dexmedetomidine and Bhutto butorphanol treatment can significantly improve the analgesic and sedative effects of patients with viral encephalitis.