国际病毒学杂志
國際病毒學雜誌
국제병독학잡지
INTERNATIONAL JOURNAL OF VIROLOGY
2015年
3期
205-208
,共4页
覃小敏%邢辉%李琳%权效珍
覃小敏%邢輝%李琳%權效珍
담소민%형휘%리림%권효진
人乳头瘤病毒%子宫颈上皮非典型增生%宫颈癌%宫颈炎%危险因素
人乳頭瘤病毒%子宮頸上皮非典型增生%宮頸癌%宮頸炎%危險因素
인유두류병독%자궁경상피비전형증생%궁경암%궁경염%위험인소
HPV%CIN%Cervical cancer%Cervicitis%Risk factors
目的 分析高危型人乳头瘤病毒(human papillomaviruses,HPV)在湖北襄阳地区妇女中的感染率及感染年龄分布情况,以及危险因素.方法 以2012-2014年间在本院就诊的4689例患者为研究对象,采用cervista酶切信号放大法检测14种高危型的HPV.其中感染高危型HPV阳性病例则进一步分析HPV感染年龄分布情况以及其在子宫颈上皮非典型增生(CIN)、宫颈癌、宫颈炎患者中的感染情况,并结合病例资料分析HPV感染危险因素.结果 4689例患者中有950例感染高危型HPV,感染率为20.26％.HPV在宫颈癌患者中的感染率最高,其次为CIN,宫颈癌相较于其他两类患者感染率对比差异有统计学意义(P＜0.05).HPV以≥55岁者的感染率最高.初次性行为年龄过早、宫颈癌家族史、多产史、经常熬夜等均是HPV感染的影响因素.结论 湖北襄阳地区HPV感染率与LARC国际癌症研究协会公布的亚洲常见HPV感染率一致.在不同年龄段中,感染率最高的年龄组为55岁以上及25岁以下,宫颈癌、CIN患者HPV感染率较高,而经常熬夜、有宫颈癌家族史、初次性行为年龄过早等因素属于HPV感染危险因素.
目的 分析高危型人乳頭瘤病毒(human papillomaviruses,HPV)在湖北襄暘地區婦女中的感染率及感染年齡分佈情況,以及危險因素.方法 以2012-2014年間在本院就診的4689例患者為研究對象,採用cervista酶切信號放大法檢測14種高危型的HPV.其中感染高危型HPV暘性病例則進一步分析HPV感染年齡分佈情況以及其在子宮頸上皮非典型增生(CIN)、宮頸癌、宮頸炎患者中的感染情況,併結閤病例資料分析HPV感染危險因素.結果 4689例患者中有950例感染高危型HPV,感染率為20.26％.HPV在宮頸癌患者中的感染率最高,其次為CIN,宮頸癌相較于其他兩類患者感染率對比差異有統計學意義(P＜0.05).HPV以≥55歲者的感染率最高.初次性行為年齡過早、宮頸癌傢族史、多產史、經常熬夜等均是HPV感染的影響因素.結論 湖北襄暘地區HPV感染率與LARC國際癌癥研究協會公佈的亞洲常見HPV感染率一緻.在不同年齡段中,感染率最高的年齡組為55歲以上及25歲以下,宮頸癌、CIN患者HPV感染率較高,而經常熬夜、有宮頸癌傢族史、初次性行為年齡過早等因素屬于HPV感染危險因素.
목적 분석고위형인유두류병독(human papillomaviruses,HPV)재호북양양지구부녀중적감염솔급감염년령분포정황,이급위험인소.방법 이2012-2014년간재본원취진적4689례환자위연구대상,채용cervista매절신호방대법검측14충고위형적HPV.기중감염고위형HPV양성병례칙진일보분석HPV감염년령분포정황이급기재자궁경상피비전형증생(CIN)、궁경암、궁경염환자중적감염정황,병결합병례자료분석HPV감염위험인소.결과 4689례환자중유950례감염고위형HPV,감염솔위20.26％.HPV재궁경암환자중적감염솔최고,기차위CIN,궁경암상교우기타량류환자감염솔대비차이유통계학의의(P＜0.05).HPV이≥55세자적감염솔최고.초차성행위년령과조、궁경암가족사、다산사、경상오야등균시HPV감염적영향인소.결론 호북양양지구HPV감염솔여LARC국제암증연구협회공포적아주상견HPV감염솔일치.재불동년령단중,감염솔최고적년령조위55세이상급25세이하,궁경암、CIN환자HPV감염솔교고,이경상오야、유궁경암가족사、초차성행위년령과조등인소속우HPV감염위험인소.
Objective To investigate the infection rate and age distribution of high-risk type HPV in Xiangyang,Hubei province,and analyze the related infection factors.Methods 4689 patients were collected as research subjects in our hospital from 2012 to 2014.Cervista HPV HR DNA test was used to detect the high-risk type HPV.For positive samples,the distraction of infection age and infection rate in CIN,cervical cancer and cervicitis were analyzed and the infection risk factors of HPV in these patients were analyzed.Results 950 cases in 4689 patients were infected with high-risk type HPV and the infection rate was 20.26％.The patients with cervical cancer had the highest HPV infection rate,followed by CIN.There was significant differences between cervical cancer patients and the other two types of patients (P ＜ 0.05).Patients above 55 years old had the highest infection rate.Early sexual behavior,family history of cervical cancer,prolificacy history,and staying up late were all the risk factors of HPV infection.Conclusions The infection rate of HPV in Hubei xiangyang area was consistent with that in Asia released by the international association for cancer research (LARC).Women above 55 and below 25 years old had higher infection rate.The cervical cancer patient and CIN patient had higher infection rate.Staying up late,family history of cervical cancer,and early sexual behavior were the risk factors of HPV infection.
